ANAEMIA Flashcards
Anaemia
reduction of haemoglobin in the blood
how do haemoglobin issues arrise
inability to make the haem (iron def)
inability to make the correct globin chains (sickle cell)
anaemia causes
- reduced production
- increased losses
- increased demand
reduced production of haemoglobin
nutrition
malabsorption
increased losses of haemoglobin
blood loss
intravascular haemolysis
increase haemoglobin demand
increased utilisation - pregnancy, growth
disease reducing iron absorption
achlorydia
coeliac disease
achlorhydia
lack of stomach acid
no conversion of non-haem iron
diseases causing iron loss
gastric erosions/ ulcers
IBD
Bowel cancer
haemorrhoids
causes of Vit B12 def
lack of intake - vegans
lack of intrinsic factor - pernicious anaemia
disease of terminal ilium
lack of intrinsic factor due to
autoimmune stomach disease (pernicious anaemia)
gastric disease
disease of terminal ilium
crohns diasease
folic acid def cause
lack of intake
absorption failure
absorption failure of folic acid cause
jejunal disease (coeliac)
abnormal globin chains
sickle cell
thalassaemia