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HUMAN DISEASE MOD 5 > ANTICOAGULANTS + ANTIPLATELETS > Flashcards

ANTICOAGULANTS + ANTIPLATELETS Flashcards

1
Q

Injectable anticoagulants

A

heparins

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2
Q

oral anticoagulants

A

coumarin
non-coumarin

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3
Q

antiplatelet meds

A

aspirin/ clopidogrel

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4
Q

heparin delivery? how long is it active for and what does it inhibit?

A

infusion
active for few mins
inhibits antithrombin 3

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5
Q

lower molecular weight heparin delivery?

A

subcutaneous injection

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6
Q

indications for anticoagulants

A

AF
DVT
heart valve disease
mechanical heart valves
thrombophilIa

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7
Q

most common anticoagulants

A

warfarin
apixaban

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8
Q

warfarin onset

A

3 days

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9
Q

warfarin mode of action

A

inhibits vit K clotting factors 2 7 9 10

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10
Q

measuring warfarin

A

INR between 2-3

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11
Q

pt taking warfarin undergoing invasive dental procedure

A

INR and FBC blood test within 72 hours
INR less than 4
treat early in day and week

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12
Q

drugs that increase INR

A

amiodarone
antibiotics
alcohol with liver disease
NSAIDs

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13
Q

drugs that reduce INR

A

carbamazepine, barbiturates
cholestryamine
griseofulvin
alcohol without liver disease

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14
Q

for pt taking warfarin do not prescribe

A

Aspirin
NSAIDs
azole antifungals

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15
Q

apixaban

A

new oral anticoagulant

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16
Q

apixaban onset

A

1 hour

17
Q

apixaban duration

A

lost within a day

18
Q

pt on apixaban with invasive dental tx

A

treat early in day and week
miss delay morning dose
restart dose immediately after

19
Q

drugs to avoid when taking apixaban

A

NSAIDS
carbamazepine

20
Q

standard antiplatelets

A

low dose aspirin 75mg
clopidogrel
dipyridamole

21
Q

antiplatelets for advanced cardiac therapy

A

prasugrel + aspirin
abciximab
eptifibate + aspirin
ticagrelor
tirofiban

22
Q

what to avoid with antiplatelets

A

additional NSAIDs
carbamazepine/ omeprazole

23
Q

clopidogrel interactions

A

erythromycin/ fluconazole reduce efficacy

24
Q

Ticagrelor interactions

A

clarithromycin may increase effect

HUMAN DISEASE MOD 5 (54 decks)

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