DMARDs Flashcards

1
Q

DMARD action

A

suppress immune system to slow or stop down disease progression, inflammatory arthritis.

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2
Q

common conditions treated with DMARDs

A

RA
Sjogrens
IBD

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3
Q

Oral med conditions treated with DMARDs

A

lichen planus
mucous membrane pemphigoid
pemphigus vulgaris
Bechet’s disease
Erythema multiforme

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4
Q

what DMARD is taken with folic acid supplementation

A

methotrexate

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5
Q

correct methotrexate intake

A

once a week with folic acid supplementation

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6
Q

methotrexate side effects

A

bone marrow suppression
mouth ulcers
neutropenia
thrombocytopenia
liver toxicity
pneumonitis

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7
Q

what DMARD is taken to treat RA

A

methotrexate

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8
Q

biologics action

A

suppress parts of the immune system

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9
Q

what would you give a pt if 2 DMARDs have failed OR they have severe RA

A

Monoclonal antibody in combination with methotrexate
- Infliximab

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10
Q

all monoclonal antibody biologics end in

A

MAB

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11
Q

what biologic is used to treat non-hogkins lymphoma

A

rituximab

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12
Q

what biologic is used to treat advanced SCC H+N

A

cetuximab

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13
Q

what biologic is used to treat H+N SCC

A

pembrolizumab

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14
Q

what biologic inhibits tumour growth

A

bevacizumab

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15
Q

what biologic is used to treat MRONJ

A

denosumab

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16
Q

what biologics are fusion proteins

A

etanercept
abatacept
aflibercept

17
Q

dental consideration of bone marrow suppression

A

neutropenia - increased bleeding risk