EPILEPSY Flashcards

1
Q

Epilepsy

A

reduced GABA levels in the brain leading to abnormal discharge of neurones

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2
Q

types of epilepsy

A

generalised - tonic/clonic, absence (petit mal)
partial - simple, complex, simple sensory

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3
Q

febrile seizure

A

affect children with fevers

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4
Q

causes of epilepsy

A

vascular disease
trauma
CNS disease; tumour, stroke, CID, meningitis, encephalitis
social; late nights, alcohol, hypoglycaemia, flashing lights

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5
Q

tonic part of seizure

A

pt has awareness of change in brain function before onset of seizure
they become stiff and lose consciousness and may fall to floor

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6
Q

clonic part of seizure

A

jerking/ contracting/ relaxing uncontrollably

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7
Q

postictal state in tonic/ clonic seizure

A

termination after 1-3 minutes
pt feels drowsy

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8
Q

status epilepticus

A

tonic clonic seizure
repeating

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9
Q

petit mal (absence) seizure

A

black out or stare into space for a few seconds
- eyelid flutter
- vacant stare
- stops activity
- loss of response

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10
Q

epilepsy precipitators

A

withdrawal/ poor med compliance
epileptogenic drugs
fatigue/ stress
infection
menstruation

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11
Q

epileptogenic drugs

A

some GA agents
alcohol
tricyclics
SSRIs

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12
Q

partial seizures

A

motor localised to one region of the brain

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13
Q

Jacksonian seizure

A

partial seizure that spreads to other motor areas

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14
Q

sensory partial seizure

A

affects any sensory modality - visual, auditory, taste, smell
often aura and may involve deja vu

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15
Q

complex partial seizure

A

automatism; repetitive purposeless movements - lip smacking, grimacing

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16
Q

preventative epilepsy tx

A

anticonvulsant drugs - valproate, carbamazepine

17
Q

anticonvulsant drug for tonic clonic

A

phenytoin

18
Q

anticonvulsant drug for absence

A

levetiracetam

19
Q

emergency epilepsy tx

A

airway and O2
benzodiazepines for status epilepticus

20
Q

valproate and benzodiazepine mode of action

A

GABA receptor actions

21
Q

Carbamazepine and phenytoin mode of action

A

sodium channel action

22
Q

surgery for epilepsy

A

removal of focal neurological lesions (benign brain tumours)

23
Q

dental aspects of epilepsy

A

fits
gingival hyperplasia (caused by phenytoin)
bleeding tendency (caused by valporate)
folate deificiency
must treat during quiescent phases

24
Q

how to assess the risk of fits

A

ask when the last 3 fits took place
ask about compliance with medication
ask about changes in medication