LIVER DISEASE

Question 1

general function of the liver

Answer 1

metabolism

Question 2

signs of liver disease

Answer 2

past history
jaundice
stigmata of chronic liver disease

Question 3

what is jaundice

Answer 3

clinically apparent hyperbilrubinaemia
bilburin >40

Question 4

what is bilburin

Answer 4

made during the process of breaking down old red blood cells

a healthy body gets rid of it

Question 5

types of liver disease causing jaundice

Answer 5

acute liver disease
chronic liver disease
jaundice secondary to biliary onstruction

Question 6

jaundice clinical features

Answer 6

pale stools
dark urine
itch
lethargy
anorexia

Question 7

chemical cause of jaundice

Answer 7

build up of conjugated bilirubin

Question 8

what is cirrhosis

Answer 8

scarring of the liver due to long term damage

Question 9

liver function tests

Answer 9

ALT/AST
ALP
GGT

Question 10

Types of hepatitis viruses

Answer 10

A B C D E

Question 11

Hep A transmission

Answer 11

faecal-oral
poor hygiene/ overcrowding
food and water contamination

Question 12

peak incidence of hep A

Answer 12

older children/ young adults

Question 13

control of hep A

Answer 13

hygiene
vaccine

Question 14

hep A presentation

Answer 14

acute illnesshe

Question 15

hep B transmission

Answer 15

blood
sex
mother to child

Question 16

type of immune response to HBV

Answer 16

humoral

Question 17

hep B presentation of chronic carrier

Answer 17

low risk of infection
do not develop liver disease
risk of hepatoma

Question 18

hepatoma

Answer 18

liver cancer

Question 19

hep B tx

Answer 19

not currently treated

Question 20

presentation of highly infectious hep B

Answer 20

progression to cirrhosis 10 years
liver failure
hepatoma

Question 21

hep C transmission

Answer 21

similar to hep B

Question 22

is there a vaccine for hep C

Answer 22

no

Question 23

HCV prevalence

Answer 23

71 million worldwide