Sketchy Pharm: Daptomycin Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Against which bacteria is daptomycin effective?

A

Gram-positive bacteria

Think of the police DePT. approaching the crowd wearing purple shirts.

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2
Q

Daptomycin targets the ________________.

A

cell wall (like the police DePT approaching the WALL of protesters)

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3
Q

What is the specific mechanism of daptomycin?

A

It inserts a lipophilic chain into the Gram-positive wall and thus depolarizes the cell.

(Think of the police DePT. tasing –depolarizing –the protesters.)

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4
Q

Daptomycin can be used on ____________-resistant organisms.

A

vancomycin (like the protester being tased into the van.)

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5
Q

Name some specific organisms that daptomycin is used to treat.

A

Vancomycin-resistant Enterococcus (represented by the drummer in front of the protesters) and MRSA bacteremia (like the defaced Pharaoh’s Chicken mascot above the motto “It’s in our blood”)

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6
Q

Daptomycin should not be used to treat _________________.

A

pulmonary infections (because surfactant chemically negates daptomycin)

(Think of the protester wearing the tazer-resistant chest plate.)

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7
Q

What is the main side effect of daptomycin?

A

Myopathy (like the police officer taking a bite out of the chicken leg)

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