Pathoma: Restrictive Diseases Flashcards
What cytokine induces fibrosis (excessive repair) in the lungs?
TGF-ß
Some medical treatments can cause interstitial fibrosis. Name two medications and one therapy.
Bleomycin and neomycin
Radiation therapy
Symptoms of idiopathic pulmonary fibrosis include __________.
progressive dyspnea and cough
Within alveolar macrophages, silicate impairs ___________.
phagolysosome formation; this results in increased risk of TB
Sarcoidosis can also affect the _________, mimicking Sjögren’s syndrome.
salivary and lacrimal glands
Noncaseating granulomas raise serum __________.
calcium
________ also presents with granulomas.
Hypersensitivity pneumonitis
Symptoms of hypersensitivity pneumonitis usually resolve with __________.
removal of the causative exposure