Respiratory & Sleep Medicine\ Pneumonitis Flashcards

(42 cards)

1
Q

What is pneumonitis?

A

Inflammation of the lung parenchyma

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2
Q

What is pneumonia?

A

Pneumonitis due to infection

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3
Q

What are some common symptoms of pneumonia?

A
  • Rigors
  • fatigue
  • cough (may be dry or productive)
  • sputum production
  • pleuritic chest pain
  • dyspnea
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4
Q

What are the common physical signs of pneumonia?

A
  • Fever
  • tachypnea
  • dullness to chest percussion
  • tactile fremitus
  • egophony
  • bronchial breath sounds
  • crackles or rales to auscultation
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5
Q

What is the pneumonia severity index?

A

A prognostic model that is used to help determine whether a patient with pneumonia should be treated as an inpatient or outpatient

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6
Q

What are the CURB-65 criteria?

A
  • It is a clinical prediction rule that uses risk factors
    • confusion
    • uremia
    • respiratory rate >30
    • BP <90/60 mm Hg and
    • age over 65
  • Predicts mortality and need for hospitalization in pneumonia
  • 0-1 factors treat as an outpatient
  • >2 factors consider hospitalization.
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7
Q

Is a positive sputum culture necessary to make the diagnosis of pneumonia?

A

No

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8
Q

Clinical suspicion plus what diagnostic test result is necessary for a diagnosis of pneumonia?

A
  • Pulmonary infiltrate on chest radiograph (obtain two views)
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9
Q

What purpose do radiographic studies serve in the management of pneumonia?

A
  • Qualify pneumonia based on location (usually singular lobar consolidation but can be multilobar or diffuse)
  • possible complications (eg, pleural effusion, pneumothorax, empyema, abscess)
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10
Q

A chest radiograph can be negative early in the disease course of pneumonia. True or false?

A

True

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11
Q

What is community acquired pneumonia (CAP)?

A

Pneumonia that is not acquired in hospital or long-term care facility

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12
Q

What is/are the first-line antibiotic(s) for CAP in the outpatient setting when no comorbidities are present, the patient has not been on antibiotics within the last 3 months, and there is a low local prevalence of drug-resistant strains?

A
  • Macrolides (azithromycin, clarithromycin, or erythromycin) are strongly recommended.
  • Doxycycline is an alternative.
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13
Q

What is/are the first-line antibiotic(s) for CAP in the outpatient setting when comorbidities (eg, heart/lung/liver/renal disease, diabetes, malignancy, alcoholism, asplenia, immune deficiency) are present and/or the patient has been on antibiotics within the last 3months and/or there is a high risk of drug-resistance?

A

A fluoroquinolone or macrolide plus β-lactum

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14
Q

What is the minimum duration of antibiotic therapy for uncomplicated CAP?

A

5 days (assuming the patient is stable and has been afebrile for more than 48 hours)

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15
Q

What is the most common bacterial cause of CAP in adults?

A

Streptococcus pneumoniae

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16
Q

What additional etiologies of pneumonia should you keep in mind for a patient with a history of the COPD and/or smoking

A
  • Haemophilus influenzae
  • Pseudomonas aeruginosa
  • Legionella
  • Moraxella catarrhalis
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17
Q

What additional etiologies of pneumonia should you keep in mind for a patient with a history of Immune suppression ?

A
  • H. influenzae
  • Pneumocystis jirovecii
  • Cryptococcus
  • Histoplasma
  • Aspergillus
  • P. aeruginosa
  • Mycobacterium tuberculosis
  • atypical mycobacteria
18
Q

What additional etiologies of pneumonia should you keep in mind for a patient with a history of Seizures

A
  • Aspiration:
    • oral anaerobes
    • gram-negative enteric pathogens
    • Staphylococcus aureus
19
Q

What additional etiologies of pneumonia should you keep in mind for a patient with a history of alcoholism?

A
  • Aspiration
  • Klebsiella
  • Acinetobacter
  • M. tuberculosis
20
Q

What additional etiologies of pneumonia should you keep in mind for a patient with a history of recent animal exposure?

A
  • Francisella tularensis (deer, rabbits)
  • Hantavirus
  • Yersinia pestis (rodents)
  • Histoplasma capsulatum (bat and bird droppings)
  • Q fever
  • Brucellosis (some farm animals)
  • H5N1 virus (poultry)
21
Q

What additional etiologies of pneumonia should you keep in mind for a patient with a history of residence or travel to the Southwest United States?

A
  • Coccidioides species
  • Hantavirus
22
Q

What patients are particularly prone to infection with S. pneumoniae?

A

Those with history of

  • splenectomy
  • sickle cell disease
  • lung disease
  • HIV, and/or
  • renal failure
23
Q

What are the most common causes of pneumonia in young, healthy adults?

A
  • Mycoplasma
  • Chlamydia
  • viruses
24
Q

What is pneumonia due to Mycoplasma/Chlamydia/Viruses called?

A

Atypical pneumonia

25
Is atypcial pneumonia more or less severe than typical pneumonia?
Generally the illness is mild
26
Do chest x-rays correlate well with the degree of illness in atypical pneumonia?
No. Chest x-rays often appear disproportionately “worse than the patient.”
27
What are the common causes of pneumonia in young children?
* RSV * parainfluenza * adenovirus * enterovirus
28
What are some common causes of bacterial pneumonia in children?
* S. pneumoniae * group A Streptococcus * group B Streptococcus (in a neonate) * M. pneumoniae * Chlamydia trachomatis * H. influenzae * M. catarrhalis
29
What is the treatment for pneumonia due to influenza A?
* Give oseltamivir or zanamivir within 48 hours of symptom onset * Consider empirical antibiotics for secondary bacterial pneumonia ( S. aureus, S. pneumoniae )
30
What are the risk factors for developing pneumonia due to S. aureus ?
* Viral pneumonia (eg, influenza) * infection via hematogenous route (ie, IV drug users or patients with infective endocarditis) * diabetes * liver disease
31
Urinary antigen test exists for what pathogens?
* Legionella * S. pneumoniae
32
What is the major water source for Legionella?
* Water distribution systems of large buildings (eg, hotels, hospitals)
33
What populations are most susceptible to Legionella pneumonia?
* Elderly * smokers * immunocompromised * travelers
34
What symptoms are common in a patient with Legionella pneumonia?
* Dry cough * fever * headache * confusion * weakness * GI disturbances (diarrhea)
35
What is the typical description for the sputum in Klebsiella infection?
Currant jelly sputum
36
Patients with what underlying diseases are at increased risk for Pseudomonas pneumonia?
* Patients with diabetes * cystic fibrosis
37
What is the most common cause of pneumonia in an HIV patient?
* Pneumocystis pneumonia (PCP) caused by P. jirovecii
38
What is the treatment for PCP?
Trimethoprim-sulfamethoxazole and steroids
39
What is the most common opportunistic infection in HIV patients?
* S. pneumoniae (same as in the immunocompetent population)
40
What causes chemical pneumonitis?
Aspiration of sterile gastric contents
41
What are the typical signs and symptoms of chemical pneumonitis?
* Dyspnea, * cough * low-grade fever * infiltrates on CXR involving dependent areas of lung
42