Renal & Urology/ Testicular Cancer

Question 1

Testicular cancer represents what percentage of cancers in males aged 15-35?

Answer 1

• 20%
• it is the most common solid tumor in this age group

Question 2

What are the two tumor cell types associated with 90% of testicular cancers?

Answer 2

1. Seminoma
2. Nonseminomatous germ cell (choriocarcinoma, embryonal, teratoma, yolk sac)

Question 3

Cryptorchidism increases the risk of testicular cancer. True or false?

Answer 3

• True
• Cryptorchidism increases the risk 40 fold

Question 4

What are signs and symptoms of testicular cancer?

Answer 4

• Painless
• firm testicular mass
• mass does not transilluminate (although a reactive hydrocele can be present)
• some patients have gynecomastia

Question 5

If testicular cancer is suspected, what imaging tests should be ordered?

Answer 5

• Scrotal ultrasound (an MRI can help if the ultrasound is inconclusive)

Question 6

What is the USPSTF recommendation regarding routine screening for testicular cancer in asymptomatic adolescent and adult males?

Answer 6

D-it recommends against routine screening

Question 7

What tumor markers should be collected in a patient with suspected testicular cancer?

Answer 7

• FBC
• beta-hCG)
• alpha fetoprotein (AFP)
• LDH