Polyomavirus JC And BK-Et Tu, BK Flashcards
What is the nucleic acid in Polyomavirus JC and BK
Circular double stranded DNA virus
What is the state of envelope in Polyomavirus JC and BK
No viral envelope present
Which condition is caused by Polyomavirus JC
Progressive multifocal leukocephalopathy (PML)
Which population is Polyomavirus JC and PML commonly seen in
Immunocompromised individuals with CD4 counts <200
What are the cause of symptoms seen in Polyomavirus JC
Demyelination of nerves (nonfocal) due to oligodendrocytes being killed
What are the clinical presentations in those patients with Polyomavirus JC
Progressive weakness due to demyelination, nonenhancing brain lesions in white matter
What are the radio graphic findings in those with Polyomavirus JC
Nonenhancing ring lesions in the white brain matter
What is the general saying for the Polyomavirus JC infection
Think AIDs patients with motor neuropathy
What is the common clinical finding in those with Polyomavirus BK
Nephropathy, hemorrhagic cystitis (red pee)
Which patients are Polyomavirus BK commonly seen in
Transplant patients, in particular those with bone and kidneys
What is the general saying fro those with Polyomavirus BK
Transplant patients with hematocrit
