Arenavirus-Welcome To The Arena Flashcards

1
Q

What is the sense and nucleic acid of the Arena virus

A

Single stranded negative sense RNA virus, but can be ambisense (positive and negative sense)

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2
Q

Where does the Arena Virus replicate

A

In the cytoplasm

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3
Q

What is the state of the envelope in the Arena Virus

A

Enveloped

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4
Q

What is the morphological shape of the viral capsid in Arena virus

A

Helical shape

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5
Q

What are the characteristics of the segmentation in the arena virus

A

2 segments

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6
Q

What does the arena virus look like under EM

A

Sandy and grainy appearance

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7
Q

How is the arena virus transmitted to humans

A

Via rodents

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8
Q

What is the example of an arena virus

A

Aka LCV or lymphocytic choriomeningitis virus

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9
Q

What are the clinical presentations of the arena virus LCV

A

Febrile Aseptic meningitis, encephalopathy, fever

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10
Q

How is the arena virus inactivated

A

Heat, low pH, irradiation, and detergents

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