Cryptosporidium-Tales From The Crypt

Question 1

Which individuals are susceptible to Cryptosporidium

Answer 1

HIV population

Question 2

What is the clinical presentation of Cryptosporidium

Answer 2

Profound watery diarrhea

Question 3

What is the method of transmission for Cryptosporidium

Answer 3

Oocytes released fecally and absorbed orally

Question 4

What are the morphological characteristics of Cryptosporidium

Answer 4

Unicellular, oocytes (cysts) in water

Question 5

Histologically, what are the characteristics of Cryptosporidium

Answer 5

Acid fast staining, looks like amethyst (pink crystals)

Question 6

What are the components of the Cryptosporidium cysts in water and how are they virulent

Answer 6

Cysts contain 4 motile sporozoites that attach to the small intestine wall and cause damage

Question 7

What is one way to prevent infection of Cryptosporidium

Answer 7

Filtration of water clears cysts, but is highly resistant to chlorination

Question 8

What is the method of treatment for Cryptosporidium

Answer 8

Nitazoxanide in immunocompetent

Spiromycin ( to approved by FDA)