Chlamydia- Pirates Of Chlam Island Flashcards
What is the result of staining for Chlamydia sp.
Gram indeterminate, does not stain
What is the location of Chlamydia sp.
Obligate intracellular bacteria
What is the feature of Chlamydia sp. that makes it an obligate intracellular bacteria
Can not make its own ATP, so requires a host to make it
What does the cell wall of Chlamydia sp. lack and what are the clinical implications
Cell walls lake muramic acid, making it unable to be treated with penicillins
What is the first stage of life cycle of Chlamydia
Elementary bodies, which is the form that enters the host. This is the infectious form as it is taken up by phagosomes
What is the second stage of Chlamydia
Reticulate bodies, which are the form inside of cells and does the replication
What will Chlamydia from under the microscope in the reticular form
Inclusion bodies
How is Chlamydia visualized
Giemsa stain
How is Chlamydia diagnosed
With the NAAT test, aka PCR
What is Rieder syndrome and what causes is
Caused by antibodies to Chlamydia:
- Reactive arthritis i knee and sacroiliac joint (cant climb)
- Urethritis (cant pee)
- Eye inflammation (cant see)
What does Chlamydia pneumonia cause
One of the three to cause atypical/walking pneumonia
What does Chlamydia psittaci cause and what is the method of transmission
Causes pneumonia and transmitted by bird droppings
What is the treatment of Chlamydia
Azithromycin (treats STI and trachomatous)
Dioxycycline (tetracycline)
Cephtriaxone (for the confection with Gonorrhea)
What treatment must be given to neonates with Chlamydia
Oral antibiotics, because the topical treatment is ineffective against the conjunctivitis
What are the subtypes of Chlamydia trachomatous and their general result
A-C: blindness
D-K: STI
L1-L3: LGV
What is the leading cause of blindness in the world
Chlamydia trachomatous
What are the clinical presentations of Chlamydia trachomatous type A-C
-Blindness
How is Chlamydia trachomatous type A-C usually transmitted
hand to eye, maybe formites
What is the most common bacterial STI in the US
Chlamydia trachomatous type D-K
What are the clinical presentations of Chlamydia trachomatous type D-K
STI with watery discharge,PID in women, passed to child in pregnant women
What is the result of congenital Chlamydia trachomatous
- child will have pneumonia
- Will have Neonatal conjunctivitis starting in 1 to weeks
- Staccato cough
How will a neonate with conjunctivitis be differentiated between chlymida and gonorrhea
Chymidia: conjunctivitis presents in 1-2 weeks
Gonorrhea: Conjunctivitis presents writhin 5 days
ChymidiaL cough is a staccato cough (quick sudden coughs)
How is Chlamydia trachomatous type L1-L3 transmitted
STI
What is the clinical presentation of Chlamydia trachomatous type L1-L3
Lymphogranuloma venerum- infection of inguinal nodes, which is tender with draining LN
