HHV8-Ring Around Kaposi Flashcards
Which illness is commonly associated with HHV8
Karposi Sarcoma
What is the status of envelope in HHV8
Viral envelope is present
What are the 3 populations that are commonly seen to have Karposi/HHV8
- Immunocompromised
- Elderly Russian Men
- Africans
What is the nucleic acid in HHV8
Double stranded DNA virus
What are the clinical presentations seen in HHV8
-violaceous lesions on nose, extremities, mucous membranes (all present as nodules, plaques, patches or macules)
Which cell origin is affected in HHV8
Mesenchymal cells involved in angiogenesis
What gives the clinical symptoms the colors commonly seen in HHV8
Proliferation of vasculature and angiogenesis
What factor is dysregulated in HHV8 to give symptoms
VEGF
What are the common lesions seen in HHV8
Hard palate (most common) Intraintestinal (seen on colonscopies)
Which B cell lymphoma is commonly see in HHV8 infections
Primary effusion lymphoma
How is HHV8 transmitted
Kissing, sexual contact (especially seen in men who have sex with men)
Which infection in HHV8 commonly confused with
Bartonella hensleae
How is an infection with HHV8 differentiate from an infection with Bartonella henslea
Bartonella henslea (a bacteria) is seen as a neutrophilic infiltrate while the HHV8 is a lymphocytic infiltrate
