HPV- Pilloma Bugs

Question 1

What is the nucleic acid in HPV

Answer 1

Double stranded DNA virus

Question 2

What is the state of envelope in HPV

Answer 2

Viral envelope not present

Question 3

What are the clinical finding of HPV 1 and 4

Answer 3

Cutaneous common warts aka verruca Vulgaris

Question 4

What are the clinical findings of HPV6 and 11

Answer 4

Laryngeal papillomatosis (recurrent respiratory papillomatosis) and (condo Loma accumulata) analgenital warts

Question 5

What is the serious cancer associated with HPV16/18

Answer 5

Squamous cell carcinoma of the anogenital region

Question 6

What stains of HPV are protected by the vaccine

Answer 6

6,11,16,18

Question 7

What is the most common STD

Answer 7

HPV

Question 8

Which part of the cell cycle is normally affected with infection of HPV 16/18

Answer 8

Transmission from G1 to S

Question 9

Which protein is affected by E7 in HPV 16/18

Answer 9

RB

Question 10

Which protein is affected by E6 in HPV 16/18

Answer 10

P53

Question 11

What is a key word in patient history that may indicate cancer from HPV

Answer 11

Postcoital bleeding

Question 12

Which finding in the Pap smear may indicate cancer from HPV

Answer 12

Koilocytes in the cervical transition zone

Question 13

What are the histological findings in koilocytes

Answer 13

Large dense nuclei, with occasional binuclear appearance

Question 14

Which population is at a higher risk of developing HPV induced cancers

Answer 14

Immunosuppressed