Plasmodium-Queens And Warlords Of Plasmodium Flashcards
What are the organisms that can cause malaria
Plasmodium malariae
Plasmodium vivax
Plasmodium ovale
Plasmodium falciparum
Where is the location that Plasmodium is commonly seen
Africa
What is the diagnosis for Plasmodium
Blood smear with Giemsa stain
What is the distuinguishing features that seperate the different Plasmodium responsible for malaria
The pattern of fever
What is the fever pattern of malaria caused by Plasmodium malariae
Quartan fever, with one on day 1 and day 4 (72 hours in between)
What is the pattern of fever in malaria caused by Plasmodium ovale and Plasmodium vivax
Tertiary fever with fever on day 1 and day 3 (48 hours in between)
What organ is affected in Plasmodium vivax and ovale
Liver, with the presence of dormant hypozoites
What is the fever pattern of malaria caused by Plasmodium falciparum
Irregular fever pattern
Malaria caused by which Plasmodium is the most severe
Plasmodium falciparum
What is the the pathogenesis of Plasmodium falciparum
Occluded blood vessels to the brain, kidneys, and lungs
What are the general clinical symptoms of Plasmodium and malaria
- Fever
- Headache
- Anemia
- Splenomegaly
What is the cause of neurological symptoms seen in Plasmodium falciparum induced malaria
Occluded blood vessels to the brain
What is the shape of Plasmodium falciparum under the microscope
Banana shaped
What is the mechanism of action of Chloroquine used to treat Plasmodium
Blocks Plasmodium heme polymerase
When would the treatment of primaquin with chloroquine be used
To removed the dormant hypnozoites in the liver
What is the treatment of Plasmodium hypozoits in the liver
Aka to treat malaria caused by Plasmodium vivax and ovale
-Primaquine
What is the treatment as a prophylaxis for Plasmodium in travelers
Palanquin and proguanil
What is the treatment for Plasmodium falciparum and serious malarial infections
Use of Artimesians (artesonate and artesimether)
What is used to treat resistant strains of Plasmodium falciparum
Quinidine
What is the vector for Plasmodium
Anopheles mosquitos
What is the life cycle of Plasmodium
Mosquitos carry sporozoites in saliva, bite and convert to trophozoits in liver. Divide into merozoits, which burst open and infect RBCs
