Strep Pyogenes (Group A)- Pie Genies' Bakery Flashcards
What is the state of capsule in Strep Pyogenes (group A)
Encapsulated with Hyaluronic acid, it is not antigenic
What is the state of growing Strep Pyogenes (group A) on blood agar plates
Beta hemolytic
What are the 3 clinical presentations of Strep Pyogenes (group A)
- Impetigo (honey crusted skin appearance)
- Strep throat and pharyngitis
- Erysipelas, red lesions/cellulitis of the the skin with well demarcated borders
What is the most common cause of erysipelas, which are red lesions with well demarcated borders
Strep Pyogenes (group A)
What are the three conditions caused by the Strep Pyogenes (group A) toxin
- Scarlett fever
- Toxic shock LIKE syndrome
- Necrotizing fasciitis
What is the toxic type that causes the toxic shock like syndrome seen in Strep Pyogenes (group A)
SpeA and SpeC (act like super antigens)
What is necrotizing fasciitis caused by
Strep Pyogenes (group A) product SpeB (which as a protease)
What are the clinical presentations of Scarlett fever and what causes it
Strep Pyogenes (group A)
- Strawberry tongue (red and swollen tongue)
- pharyngitis
- widespread rash that spares the face
What is the main virulent protein in Strep Pyogenes (group A)
M protein
What condition in Strep Pyogenes (group A) does the M protein cause
Rheumatic fever
What is the function of protein M in Strep Pyogenes (group A)
Interferes with opsonization and phagocytosis
What is the serious complication caused by Strep Pyogenes (group A) M proteins
Molecular mimicry leads to antibodies inking to myosin heavy chains in the heart, leading to mitral valvular damage
Will treatment of Strep Pyogenes (group A) help to prevent rheumatic Fever
Yes
What is the pneumonic for Strep Pyogenes (group A) rheumatic fever symptoms and what does it stand for
Jones
J-Joints caused by poly arthritis
O-(heart shaped) heart issues in endocarditis and myocarditis
N-Nodules on extensors surfaces
E-Erythema margintum (well marginated borders)
S-Syndenham’s chorea (involuntary movements)
What is Sydenham’s chorea and what causes it
Strep Pyogenes (group A) causing involuntary movement of the hands and face
What type of hypersensitivity is rheumatic fever
Type 2
What type of sensitivity is post streptococcal glomerulonephritis
Type 3
Will treatment of Strep Pyogenes (group A) impetigo prevent rheumatic fever and poststreptococcal glomerulonephritis
Will prevent Rh, but not PSGN
What are the clinical presentations of Strep Pyogenes (group A) caused poststreptococcal glomerulonephritis
- Puffy cheeks due to edema caused by nephritis
- Dark Coke colored urine
When with poststreptococcal glomerulonephritis present after a Strep Pyogenes (group A) infection
2 weeks
What is the treatment for Strep Pyogenes (group A)
Penicillin
What are the three virulent factors in Strep Pyogenes (group A)
- Streptolysin O
- Streptokinase
- DNAses
Which organism will cause necrotizing fasciitis
Strep Pyogenes (group A)
What is the function of streptolysin O in Strep Pyogenes (group A)
Allows Strep Pyogenes (group A) to be beta hemolytic
