Corynebacterium Diphtheriae-Corazon De La Corrida Flashcards
What is the result of a gram stain of Corynebacterium Diphtheriae
Gram positive
Is Corynebacterium Diphtheriae a spore former
No
What is the morphological characteristic of Corynebacterium Diphtheriae
Club shaped with a V or Y shape
What is the staining that Corynebacterium Diphtheriae will show and what are the colors
Meachomatic granules will stain red with aniline dyes, while the rest of the cell will be blue
In the toxin produced by Corynebacterium Diphtheriae, what are the functions of the different subunits
A-active component
B-Binding component
What is the mechanism of action of the diptheria toxin
Causes ribosylation of Elongation factor 2, which inhibits ribosome activity and subsequent cell death
What is the result in the oropharynx as a result of Corynebacterium Diphtheriae infection
Pseudomembranous exudate
What is the method of transmission for Corynebacterium Diphtheriae
Respiratory droplets
What are the clinical presentations of Corynebacterium Diphtheriae infection
- Bulls neck (thickening of the neck)
- Airway obstruction and lymphanopathy
- myocarditis, arrhythmias, and heart block
- Demyelaniation of nerve fibers
In the demyelination of nerve fibers in Corynebacterium Diphtheriae, where is the starting location and what is affected
Starts in the oropharynx and works to the other cranial nerves
What is the plating media used for diagnosis of Corynebacterium Diphtheriae
Tellurite and Loeflers media
What is the testing method used to determine if a strain of Corynebacterium Diphtheriae is toxic or not
Eleks test (paper contains antitoxin)
Which populations are most likely to get Corynebacterium Diphtheriae
Immigrants due to lack of immunization
