Clostridium Perfringens-Private Ringen Motorcycle Crash

Question 1

What is the result of gram staining Clostridium Perfringens

Answer 1

Gram positive

Question 2

What are the two common conditions seen with Clostridium Perfringens infection

Answer 2

Motorcycle accidents and battle wounds (large amounts of flesh in contact with soil)

Question 3

What allows Clostridium Perfringens to infect

Answer 3

Forms spores in the dirt, and are able to infect

Question 4

What are the clinical presentations with Clostridium Perfringens cutaneous infections

Answer 4

Gas gangrene, aka clostridial myonecrosis, which is gas formation under the tissue that causes a cracking sound on palpation

Question 5

What is the virulance of Clostridium Perfringens that allows for clostridial mypnecrosis

Answer 5

Alpha toxin, which allows the lysis of RBCs via lecithiinase, which cleaves lecithinase (a phospholipid)

Question 6

What is the result of plating Clostridium Perfringens on a blood agar

Answer 6

Causes a double zone of hemolysis, which is unique

Question 7

What is the clinical presentation of Clostridium Perfringens when ingested

Answer 7

Slow onset of food poisoning, since spores are ingested, and must reproduce in the gut to form the toxins

Question 8

What is the treatment for Clostridium Perfringens

Answer 8

Penicillin