Paramyxovirus-Paranormal Mixer Flashcards
What is the sense and nucleic acid of Paramyxovirus
Single stranded negative sense RNA
Where is the location of replication for the Paramyxovirus
Cytosol
What is the status of the envelope in Paramyxovirus
Viral envelope present
What is the alternate term for Measles
Rubeola
What are the symptoms of the prodromal Paramyxovirus measles virus
4 C’s Cough Conjunctivitis Coryza (runny nose) Koplic spots
What are Koplic spots and what are they indicative of
Blue/white spots in a read background located in the mucosa near the molars. This is indicative of measles/rubeola
What is the characteristic of the fever seen in measles
> 104 for four days
What is the rash seen in measles
Maculopapular rash that starts on the head and works down, usually in a confluence pattern (like a dress and continuous
What are the complications seen as a result of measles
Pneumonia, subacute sclerosing pan encephalitis
What is subacute sclerosing pan encephalitis and what causes it
Caused by measles
-inflammation of the brain and may arise anytime, even years after the infection
What are the virulence factors for measles
Fusion proteins
HA
What do fusion proteins do
Cause multinucleated giant cells (aka Wartharin finkeldey cells) to have red occlusions, usually in lymphoid tissues
What can be given to help decrease the complications of measles
Vitamin A
What is the clinical presentation of mumps
Inflammation of the parotid glands and testes
What are the complications of mumps
Inflammation of the epiglottis can lead to infertility and testicular trophy, as well as testicular cancer
-meningitis
Which virulance factor does mumps contain
Fusion protein, NA, HA
What family is the measles, mumps, RSV, and parainfluenza part of
Paramyxovirus
How does the respiratory syncytial virus (RSV) infect
Attaches to G protein to invade the respiratory cells
What are the complication of RSV
Broncholitis, Pneumonia
What is the number one cause of pneumonia and broncholitis in infants
SRV
How is RSV treated
Ribavirion in adults
IgG monoclonal antibody known as Palivisumab
Which condition can result in the seal cough and steepling on the X-RAY
Parainfluenza
