Perio III Flashcards
There are more bacteria than cells in a human body by a factor of _____
20
Undisturbed oral biofilm grows at ____to _____ micrometers/day
82 - 200
T/F
CHX can affect plaque that’s been in place from 24-48 hours.
T/F
CHX can affect 6 hour plaque
False
True
If PD is over 7mm, what is the average reduction in PD after Scaling and Root Planing?
2.16 mm
If PD is over 7mm, what is the average reduction CAL after Scaling and Root Planing?
1.19 mm
What is the main function of Scaling/Root Planing?
Decreases surface area
What is the deepest Scaling and Root Planing generally goes on the root?
5 mm
*even if PD much bigger than 5 mm
6 problems of Restricted Access when Scaling/Root planing
PD
Furcations
Root Proximity
Root Flutings
CEJ relationships
Restorations
Periodontal _____ lesions can limit soft tissue management
Infrabony
Perio OHI clinical protocol:
3 items
Electric toothbrush
Waterpik (or floss)
CHX 2x/day
SRP is part of Perio clinical protocol and is done with ______
local anesthesia
What low dose antibiotic is preferred?
What is the dose?
Doxycycline
20 mg
When is the re-eval post-SRP?
4-6 weeks
At 4-6 weeks SRP, what sites are re-treated after re-eval?
In what 2 ways?
greater than 5 mm
SRP, Site-specific drugs
When are surgical treatments considered in the Perio Clinical Protocols?
Post re-eval, after second SRP, site specific drugs, etc if response not achieved
Low Dose Doxycycline (originally Periostat) is 20 mg doxy, _____ tabs, every ____ hours
180 tabs
12 hours
20 mg concentration of doxy has no bacterial effect, but does chelate metals (Ca, Zn, Mg) and inactivates ________
Matrix metalloproteinases
The matrix metalloproteinases inactivated by low dose Doxy are what 2 specific products?
Produced by what 2 specific cells?
Gelatinases, Collegenases
PMN’s, Macrophage
*so low-dose Doxy fights our own immune system and its degrading factors
When is it appropriate to use SRP + Local delivery?
Post re-eval
6 conditions SRP + local delivery can be used:
Pockets greater than 5mm
Maintenance PD 5-6mm
Early perio abscess
PD distofacial 2M’s for 3M extraction
Ailing implants
Furcations
3 locally delivered Antimicrobials (brand names)
PerioChip
Atradox
Arestin
What is in PerioChip:
Atradox:
Arestin:
CHX
Doxycycline (gel)
1 mg minocycline (powder)
T/F
In terms of reaching the disease site, achieving adequate concentration and duration, killing the target microbe, and not harming the patient, Locally Delivered antimicrobials are the best
(when compared to mouth rinse, subgingival irrigation, and systemic antibiotics)
True
Arestin is __mg of _____ in powder
1 mg
minocycline
GCF concentration minocycline after Arestin therapy:
3 days out:
14 days:
28 days:
90,000 ug/ml
3250 ug/ml
340 ug/ml
10-20 ug/ml
5 bacteria that are susceptible to minocycline (Arestin) concentrations at 2-8 ug/ml
P. gingivalis
P. intermedia
F. nucleatum
E. corrodens
A.a.
Low dose doxy targets cytokines, prostanoids, MMP’s and therefore inhibits _____ and _____ metabolism
CT
bone
T/F
Local antimicrobial + Low Dose Doxy goes after both microbial challenge and CT/Bone metabolism
True
It is possible to get a pocket reduction of 3mm, but more realistically it will be ____mm.
Pocket reduction of ___mm is not realistic
2mm
4mm
Open Flap Debride can get a Pocket Reduction of ___mm
3.00
SRP + Arestin reduction in PD:
SRP + Atridox:
SRP + PerioChip:
- 65 mm
- 2 mm
- 9 mm
(bout half mm less reduction in CAL)
What systemic antibiotic is the drug of choice in treatment of Agressive Perio?
Amoxicillin
Other than Amoxicillin, name 6 drugs prescribed for Aggressive Perio:
Metronidazole (NOT w/ EtOH)
Tetracycline (photosentitive)
Doxy
Clindamycin
Amoxicillin + Clavulanic Acid (Augmentin)
Azithromycin (Z-pak not used much any more)
T/F
The advantages of systemic antibiotics is wide dispersement, reduction of chair time to treat pts, and a wide range of drugs to choose from.
True
What is the primary disadvantage to systemic antibiotic use for chronic perio?
pt compliance
Aside from compliance, allergy, GI problems, DDI’s, cost and the inability to penetrate intact ______ are disadvantages for systemic antibiotic use for chronic perio.
biofilm
T/F
Frequency (of taking drug) and compliance are inversly related
True
GI, nausea, photosensitivity, bacterial resistance, _____, and ______, are common side effects of systemic antibiotics.
Esophagitis
Candidiasis
Name 4 antibiotics commonly prescribed for systemic use in perio
Tetracycline
Doxycycline
Minocycline
Amoxicillin
Systemic antibiotics has a positive effect on ____
CAL
What antibiotic combination has the greatest effect on CAL?
This reduces CAL by ___mm
Best results are obtained when prescribed for ____ days
Amoxicillin + Metronidazole
0.4 mm
7
*either aggressive or chronic
T/F
Systemic antibiotics should be used in most pts with periodontitis
False
Systemic antibiotics should be used in conjunction with _____ treatment over a period of 7 days
SRP
SRP + Arestin decreases ______ and _______
hsCRP
IL-6
SRP + low dose Doxy degreases what 4 things?
MMP’s
hsCRP
HDL
apolipoprotein-A
Most changes in a perio Tx plan occur when?
Re-evaluation
After all non-surgical therapy is considered in the Re-Evaluation, what are the 3 options?
Control Etiology (or modifying factors)
Surgical Therapy (phase II)
Compromised maintenance therapy
When should the pt proceed to a Maintenance Phase?
When Stable
If the pt is not stable upon re-evaluation, then proceed to…
Personalized re-treatment
What are the 3 options in Personalized Re-treatment?
Antimicrobial therapy
Surgery
Combination
What is the most critical phase of successful periodontal therapy?
Maintenance
Maintenance visit: If PD is stable with no BOP, then Tx is routine - review OHI with same recall interval. If PD same but BOP is present, what is the Tx course?
OHI
SRP on bleeding sites
Consider - local antimicrobials
Consider - shortening recall intervals
Maintenance visit: PD and BOP increase
4 things
OHI
SRP
Adjuctive therapy (local/systemic antibiotics)
***Refer to Periodontist
Why is Perio maintenance interval 3 months?
Re-infections of pockets happens around 3 months
(60+ days)
*referrals tend to alternate GP/Periodontist
The only exception to initiating Tx without a Tx Plan:
Emergencies
A Tx Plan is a working ______
Document
An emergency begins a Treatment Plan at the _____ phase
Urgent
After the Urgent Phase is the ______ Phase
Control
Emergency therapy
Initial therapy
Determine Response:
Corrective:
Regular re-care examinations (reassessments):
Urgent Phase
Control Phase
Re-evaluation Phase
Definitive Phase
Maintenance Phase
What is the Initial Therapy (Phase I) for Gingivitis?
Med consult (if needed)
OHI
scale and polish
re-eval 4-6 wks
phrophylaxis every 6 months if disease resolved
Mild Chronic Periodontitis has Inflammation extending to the ______.
Attachment loss ____mm from CEJ
PD ____mm
Radiographic bone loss less than ____%
furcation:
bone
1-2mm
3-4mm
20%
Class I or no furcation involvement
Initial (phase I) therapy for Mild Chronic Periodontitis:
Med consult (if needed)
OHI
SRP w/ anesthesia
2-4 appointments
Re-eval 4-6 weeks
3-4 month maintenance interval (depending on OH)
Moderat Chronic Periodontitis has inflammation extending to the _____.
Attachment loss ___mm from CEJ
PD ___ mm
Radiographic bone loss ___% to ___%
Furcation involvement
Mobility:
bone
3-4 mm
5-6 mm
20%-40%
Class I or II furcations
Class I and II mobility
Moderate Chronic Periodontitis Initial Therapy (Phase I):
Med consult if indicated
OHI
SRP
2-4 appointments
Re-eval 4-6 weeks
Locally delivered antimicrobials in 5-6mm pockets
Periodontist referral
Advanced Chronic Periodontitis has inflammation extending to the bone, bleeding on provocation, attachment loss greater than ___ mm from CEJ
PD greater than ___mm
Radiographic bone loss greater than ___%
furcation
mobility
5 mm
7 mm
40%
Class I, II, or III furcation
Class I, II, or III mobility
Advanced Chronic Periodontitis: Med consult if needed, OHI, SRP, 2-4 appointments, Re-eval in 4-6 weeks, locally delivered antimicrobials in ___mm residual pockets, and referral to periodontist
***this is exactly the same treatment as Moderate Chronic Periodontitis
5-6 mm
What is prognosis without treatment?
What type of prognosis takes into account what effect the periodontal treatment will have on the course of the disease?
Diagnostic prognosis
Therapeutic prognosis
What type of prognosis anticipates the results of perio treatment and forecasts for the success of a prosthetic restoration?
What prognosis is given prior to the initial phase of Treatment and may change according to the patient/tooth response?
Prosthetic prognosis
Provisional prognosis
Prognosis is divided into:
Overall prognosis
Individual tooth
What is the single most important factor in the Overall Prognosis/Systemic Background?
Smoking
Cigaretts smokers are __-___ times more likely than non-smokers to develop severe periodontitis
5 to 8 times
What 3 positive effects does 20 Minutes smoking cessation have?
BP drops to normal
Pulse rate drops to normal
Peripheral body temp increases to normal
What positive effect does smoking cessation have at 8 hours?
At 24 hours?
CO drops to normal
Chance of heart attack decreases
What positive benefit is seen related to smoking cessation at 2 weeks - 3 months?
At 1 to 9 months?
Circulation improves, lung function increases 30%
Coughing, sinus probs, breathing improve and Cilia Re-Grow
What positive benefit is seen by smoking cessation at 1 year?
5 years?
Heart disease reduced 50%
Lung, oral, pharynx, esophageal cancer decreased 50%
*stroke reduced to non-smoker in 5-15 year range
What positive benefit is seen by smoking cessation at 10-15 years
Lung cancer similar to nonsmoker
heart disease like nonsmoker
What bacteria is increased by Type I diabetes?
What bacteria is increased by Type II diabetes?
Captocytophaga spp.
P. gingivalis
What 2 consequences does diabetes have in the GCF?
Decreased PMN function
Increase glc
What vascular changes are seen in diabetes?
Increased thickness
*decreases oxygen diffusion and waste elimination
How does diabetes impair wound healing?
Stimulates collegenase and alters collagen metabolism
Also limits production of Growth Factors
Untreated moderate/advanced periodontitis pt loses ___ teeth/yr
Treated w/ no maintenance loses ___ teeth/yr
Treated w/ maintenance loses ___ teeth/yr
- 36
- 22
- 11
Perio treatment is ___x as effective as no treatment
3.5x
T/F
The level of oral hygiene at 1st treatment isn’t as important as the level of OH at completion of initial phase of Tx (Phase I)
True
T/F
An inflammatory response and plaque calculus suggests a better prognosis
True
What has a better prognosis, chronic infection or perio abscess?
Abscess
In SRP, what is the instrumentation limit?
Curette efficiency:
- 52 mm *most of time calculus over 5 mm remains
3. 73 mm
T/F
PD is more important than CAL when determining prognosis
False
*invert - prognosis based on CAL
The ratio for a tooth with an average root length (13mm) is:
1:2
Individual tooth Prognosis Class I:
Class II:
Class III/IV:
Fair
Questionable
Poor/Hopeless
Prognosis based on tooth mobility
Class I:
Class II:
Class III:
fair (slight mobility)
questionable
hopeless (severe mobility + depressive)
What’s worse, a single rooted mobile tooth or multi rooted mobile tooth?
Multi-rooted tooth is worse
T/F
Prognosis can be Good, Fair, Poor Questionable, and Hopeless
True
T/F
Maxillary molars are lost more frequently than mandibular molars
True
The average tooth loss with furcations over a 20 year period is what?
35.7%
What is the Periodontal Treatment plan for someone that had PD of 3 mm?
Fluoride
*no SRP