Histology - 514-2 Flashcards

1
Q

T/F

The volume of cells exceeds the volume of extracellular matrix in connective tissues.

A

False.

The extracellular matrix is much greater.

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2
Q

Name four types of connective tissue

A

Ebryonic
Connective tissue proper
Specialized
Supporting

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3
Q

What is an example of embryonic connective tissue?

A

Mesenchymal

also mucous

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4
Q

Name four kinds of CT Proper.

A

Loose
Dense (regular and irregular)
Reticular
Elastic

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5
Q

What is an example of specialized CT?

A

Adipose tissue

also hematopietic

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6
Q

What are two types of supporting CT?

A

Cartilage (hyaline, elastic, fibrocartilage)

Bone

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7
Q

What are all connective tissues derived from?

A

Mesenchyme

embryonic mesenchymal cells

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8
Q

Which connective tissue cell is most abundant?

A

Fibroblasts

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9
Q

Why fibroblasts, not fibrocytes?

A

Because they are so transformable.

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10
Q

From what cell is a macrophage derived?

A

Monocyte

type of WBC - leukocyte

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11
Q

Trace the cell differentiation that results in an osteoclast

A

(working backwards)

Osteoclast - macrophage - monocyte - hematopoietic stem cell - mesenchyme

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12
Q

T/F

Extracellular matrix is found in epithelia

A

False

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13
Q

What is ground substance

A

component of ECM / gel-like amorphous subst

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14
Q

What characterizes Reticular Fibers

A
Type III collagen
Spongy tissue (bv walls)
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15
Q

What characterizes Elastic Fibers?

A

made from Elastin

can stretch 150% resting length

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16
Q

What is the most abundant type of collagen?

A

Type I

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17
Q

What type of collagen is a gel-like substance?

A

Type IV

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18
Q

What type of collagen is abundant in the placenta?

A

Type V

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19
Q

Which collagen forms anchoring loops in the basal lamina?

A

Type VII

20
Q

What collagen is found in Descement’s membrane in the cornea?

A

Type VIII

21
Q

What collagen type is found in mineralizing cartilage?

A

Type X

22
Q

What cell produces collagen?

A

Fibroblasts

23
Q

What are the steps of collagen production?

A

Preprocollagen - pro collagen - tropocollagen - collagen fibrils

24
Q

What step is Vitamin C dependent?

A

Preprocollagen - procollagen

enzymes depend on C to put into triple helix

25
Q

Does tropocollagen have end strands?

A

No - end strands are removed at this stage

26
Q

What can bind ECM ground substance to integrin proteins?

A

Glycoprotein

27
Q

What does “areolar” mean?

A

loose

28
Q

What are the four kinds of connective tissue proper?

A

Loose
Dense (regular and irregular)
Reticular
Elastic

29
Q

How do Mast Cells “dilute” an area of infection?

A

Release histamine (vasodilator)

30
Q

Where are type III collagen fibers found?

A

Reticular CT

31
Q

T/F

Elastic fibers are branched

A

False

32
Q

What’s going on with Ehlers-Danlos Syndrome that allows for unusually elastic skin?

A

Defective Collagen synthesis.

33
Q

What kind of adipose tissue is multilocular?

A

Brown

34
Q

What can be considered intracellular CT?

A

Adipose tissue

35
Q

What kind of fat gets its name from an organelle?

A

Brown - because it is loaded with mitochondria.

36
Q

Name 3 kinds of cartilage and 2 kinds of bone

A

Hyaline, Elastic, Fibro-

Compact and Spongy

37
Q

What membrane surrounds cartilage?

A

Perichondrium

38
Q

What are chondroblasts surrounded by matrix?

A

Chondrocytes

39
Q

All cartilage contains what type of collagen?

A

Type II

40
Q

What type of cartilage is the template for endochondral bone formation?

A

Hyaline

41
Q

What additional ingredient does elastic cartilage contain?

A
Elastic fibers
(found in external ear / epiglottis)
42
Q

T/F

Elastic Cartilage has no perichondrium.

A

False

43
Q

What type of cartilage is found in the TMJ?

A

Fibrocartilage

Resists compressing and absorbs shock

44
Q

What type of collagen is found in the TMJ

A

Type I and II

Type II only in hyaline/elastic

45
Q

What’s another name for spongy bone?

A

Trabecular