Oral Soft Tissues II Flashcards

1
Q

T/F

The normal periodontium has little to none Sulcular/Gingival Crevicular Fluid

A

True

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2
Q

How much Gingival Crevicular Fluid (sulcular fluid) is there without gingivitis?

A

0.42 - 1.56 microliters

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3
Q

What type of Antibodies are in sulcular fluid?

A

IgG

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4
Q

What are 3 defense mechanisms of the Gingiva?

A

Sulcular fluid

Leukocytes

Saliva

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5
Q

What antibodies are found in Sulcular Fluid?

A

IgG

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6
Q

T/F

Smoking increases Sulcular Fluid

A

True

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7
Q

T/F

More than 90% of Leukocytes in the gingival sulcus are PMN’s

A

True

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8
Q

T/F

Glycoproteins and mucoids are serve as lubrication and physical protection in the saliva

A

True

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9
Q

What is the major antibody of the Saliva?

Of sulcular fluid?

A

IgA

IgG

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10
Q

What are 2 antibacterial components of Saliva?

A

Lysozyme

Lactoperoxidase (oxidize susceptible bacteria)

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11
Q

Gingival Inflammation:
How many days for Initial lesion?

Early lesion?

Established lesion?

A

2-4 Days

4-7 Days

14-21 Days

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12
Q

The initial lesion (2-4 days) sees a rise of what?

A

Increase in Gingival Cervicular Fluid

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13
Q

T/F

Gingival Bleeding is Cell rich and Collagen poor and is defined by a sulcular ulceration

A

True

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14
Q

What are 3 types of Generalized gingivitis?

A

GM - gingival margin

AG - atached gingiva

Papillae

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15
Q

T/F

Chronic inflammation of the Gingiva progresses from Papilla to Gingival Margin to Attached Gingiva

A

True

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16
Q

What can cause a local color change of the gingiva?

Systemic?

A

Amalgam

Heavy metals

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17
Q

T/F

The consistency of gingival tissue from health to chronic inflammation proceeds from Firm > Edematous > Fibrotic

A

True

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18
Q

T/F

Two types of Chronic Inflammation are Plaque associated and Mouth breathing

A

True

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19
Q

T/F

Two types of Acute Inflammation of the gingiva are Gingival Abscess and Periodontal Abscess

A

True

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20
Q

T/F

Drug-induced Enlargement of the gingiva is a type of Hyperplasia

A

False

*just enlargement

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21
Q

Where does Drug-Induced enlargement of the gingiva begin?

A

Interdental papilla

*extends to facial/lingual margins

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22
Q

3 features of Pathogenesis of Anticonvulsant gingival enlargement:

A

Fibroblast proliferation

Collegenase deactivation

Plaque-induced inflammation

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23
Q

T/F

The dose of Anticonvulsant is responsible for amount of gingival enlargement

A

False

*dose response doesn’t seem to matter

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24
Q

What is more vascular in nature, an enlargement caused by Phynytoin (anticonvulsant), or one cause by Cycolsporine/Tacrolimus (immunosuppressants)>

A

Cyclosporine/Tacrolimus

*Also appears to be dose related

**Expressed in 20-70% of pts taking drug - wow

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25
What has less overgrowth, Cyclosporine or Tacrolimus | (immunosuppressants)?
Tacrolimus
26
Name 3 Calcium channel blockers:
Nifedipine Diltiazem Verapamil
27
T/F | Kidney transplant pts can be on Verapamil + Cyclosporine (Ca blocker and immunosuppressant)
True
28
What are the 3 categories of gingival enlargements associated with systemic conditions?
Conditioned Neoplastic False
29
What are 3 types of Conditioned gingival enlargements?
Hormonal Nutritional Allergic
30
T/F Pregnancy causes gingivitis T/F Prevotella intermedia has been associated with pregnancy
False True *only predisposes - accentuates response to plaque **begins in 2nd-3rd month
31
The pregnancy tumor that needs to be treated is called what? From whence does it come?
Pyogenic Granuloma Interdental papilla
32
Name the 4 nutritional influences of Gingiva:
Ascorbic acid - (collagen production) Folic acid Vitamin B12 Protein Deficiency
33
T/F | No nutritional deficiencies by themselves cause gingivitis or periodontitis
True
34
T/F The Perio treatment phases consist of: Phase 1 Initial (soft tissue) Re-evaluation (4-6 weeks) Phase 2 surgical (hard tissue) Maintenance
True
35
Describe the 1st Phase of Perio treatment:
SRP - Scaling and Root Planing OHI - Oral Hygiene Instruction
36
When is Scaling and Root planing done in Perio treatment?
Phase 1: Initial (soft tissue) therapy
37
Attached Gingiva =
Keratinized Gingiva - Probing Depth or Gingival Margin to MGJ minus Probing Depth
38
T/F | If the GM is above the CEJ, the value is negative
True
39
CAL =
GM to CEJ (+ or -) + Probing Depth
40
Name 3 cell types found in the gingiva:
Squamous Epithelium Keratinocytes Nonkeratinocytes
41
What are the 3 Nonkeratinocytes found in the gingiva?
Melanocytes Langerhan's cells (antigen presenting) Merkel cells (free nerve endings)
42
5 Gingival Fibers:
Circular Dentogingival Dentoperiosteal Alveologingival Transseptal
43
5 Perio Fiber:
Alveolar Crest Horizontal Oblique (occlusal forces - largest group) Apical Interradicular
44
T/F | The MGJ does not change throughout a lifetime
True
45
What is the line of demarcation of the MGJ?
Alveolar Mucosa Attached gingiva *keratinized to non-keratinized
46
What is the effect of smoking on the Gingival Crevicular Fluid?
Immediate transient increase in GCF *smoking event = increase in crevicular fluid
47
Gingival Crevicular Fluid's other name:
Sulcular fluid
48
T/F | Periotron analyzes sulcular/GCF after tested with filter paper (threads or micropipette)
True
49
GCF is present in _____ amount in healthy people and _____ amount in people with gingivitis
Small Larger
50
GCF is composed of proteins, Antigen, enzymes, epithelial cells, leukocytes, electrolyte, organic compounds, and ______
Antibody - IgG
51
T/F GCF increases with circadian rhythm (6 AM to 10 PM), sex hormones, chewing, smoking (immediate), and initial pathogenesis
True
52
What are the 2 names for the Anti-convulsants? Mechanism of gingival enlargement? Dose dependent?
Dilantin/Phenytoin Fibroblast proliferation/collagenase inhibition no/questionable
53
Name 3 Ca channel blockers:
Nifedipine Diltiazem Verapamil
54
Name 2 Immunosuppressants: Compare to Phenytoin: Dose dependent?
Cyclosporine/Tacrolimus More vascular yes
55
Describe the Initial, acute, 2-4 day gingival inflammation:
PMN's, macrophage, increased crevicular flow, no gingivitis
56
Describe the Early, 4-7 day gingival inflammation:
T-cell gingivitis - red, bleeding, edema
57
Describe the Established, 2-3 week gingival inflammation:
B-cell Plasma cells chronic
58
Describe the Advanced stage of gingival inflammation:
Periodontitis (alveolar bone loss and pocket formation) B-cell lesion
59
Name 3 categories of Plaque-Induced disease:
Systemic factors (puberty, blood dyscrasias) Drugs Malnutrition
60
Non-plaque induced disease includes E. coli, Strep, Neisseria, Treponema, Dandidiasis, Histoplasmosis, and ______.
Herpes *also trauma, genetic, systemic disease
61
What is the most prevalent form of Periodintitis in adults?
Chronic
62
Localized chronic periodintitis means
30 *also Generalized and Diffuse (GM + papilla)
63
CAL severity: Slight: Moderate: Severe:
1-2 mm 3-4 mm 5+ mm
64
Localized Aggressive Periodontitis occurs at what sites?
Molars and Incisors
65
Aggressiv Periodontitis is more common in African Americans and is associated with what bug? What 2 cytokines are elevated?
A.a. PGE2 and IL-1b
66
T/F Periodontal abscesses has pocket association and PMN accumulation. T/F Gingival abscesses have pocket formation and bone loss
True False *no bone loss or pocket **Gingival abscess NOT a cyst, but bacteria have been carried into gingival tissue
67
T/F Periodontitis associated with Pregnancy sees an increase in GCF, and complications can see preterm labor and low birthweight.
True
68
4 General risk factors for Periodontal Disease?
Microbial Systemic Behavioral Local
69
What are the bugs involved in NUG and NUP?
P. intermedia Spirochetes Fusiform bacteria
70
T/F NUG proceeds by: forming pseudomembrane, replacing epithelium with meshwork of fibrin, necrotic epithelial cells, PMN's, etc.
True
71
What forms an interdental crater by punching out papilla?
NUG
72
Describe the treatment for NUG:
1st - debridement, Oral Hygiene Instruction 2nd - 1-2 weeks, OH 3rd - 4-6 weeks, possible gingivectomy *Amoxicillin/Metronidazole (clindamycin if allergic)
73
How does NUP differ from NUG?
Bone loss *Systemic signs usually immunosuppression ** very painful
74
Where can primary herpes (HSV-1) occur?
Bound and Unbound tissue *attached keratinized and alveolar
75
All sexes and races are equally affected by HSV
True
76
What are 3 drugs used to treat HSV? Other than topicals Acyclovir (zovirax), Penciclovir (Denavir), Docosanol (Abreva)
Acyclovir Cibraadine Valacyclovir
77
4 Phases of HSV infection
Prodromal (gingival inflammation, fever, etc) Active (vesicles, shedding, etc) Latency (back to ganglia) Reactivation (stress, sun, etc)
78
What is the term for extra-oral Herpes?
Herpes labialis
79
Recurrent herpes occurs where in the mouth?
Bound down tissue (attached gingiva) *grape cluster presentation
80
What is hand herpes?
Whitlow *acyclovir
81
T/F | Aphtous ulcer is not herpes although it looks similar (has a different etiology)
True
82
T/F | Stippling is found in 35% of children between 5-13
True
83
What is the mean gingival sulcus depth in pediatric pts?
1 mm *also no papilla due to wide spacing
84
Describe the PDL in pediatric pts?
Wider than adults
85
Name 4 diseases that alter the oral mucosa/gingiva in pediatric pts:
Varicella Rubella (measles) Scarlatina (scarlet fever) Diphtheria
86
What is the most prevalent gingival disease in childhood?
Chronic marginal gingivitis (looks like chronic) *associated with tooth eruption
87
If the base of the pocket is coronal to underlying bone it is ______, it the pocket is apical to adjacent bone it is _____. What type of bone loss occurs with each?
Suprabony - Horizontal bone loss Intra/infrabony - Vertical bone loss
88
T/F | Elimination of plaque is the rationale behind pocket reduction therapy
True
89
A "window" into a bone is a _______ Further loss of facial Alveolar bone is ______
Fenestration Dehiscence
90
Fenestrations are a development flaw, not active PD
True
91
What are the 4 Patterns of Bone Loss?
Horizontal Vertical Osseous crater Reverse architecture
92
What is the most common destructive pattern of bone loss?
Horizontal
93
What pattern of bone loss has the best chance of regeneration?
3 wall defect
94
T/F | A 4 wall defect resembles a tooth extraction and doesn't exist in natural dentition
True
95
T/F | 1 wall defects and horizontal bone loss can't be grafted
True
96
Angular or U-shaped defects are known as ______ architecture.
Reverse
97
Concavities in the crest of the Alveolar bone that are confined within facial and lingual walls are know as...
Osseous craters
98
Primary Occlusal Trauma occurs when excessive forces are applied to tooth with ______ Secondary Occlusal Trauma occurs when normal/excessive forces are applies to a tooth with ______
Normal periodontium Reduced periodontium
99
T/F | Occlusal trauma can cause periodontal pockets and attachment loss
False
100
Describe consequences of Hypofunction: | 4 things
PDL atrophy PDL space narrows Cementum increases thickness Alveolar bone thins
101
T/F The difference between Localized Aggressive Periodontitis and Generalized Aggressive Periodontitis is based on location and number of teeth involve, NOT on percentage of sites.
True
102
5 common PD pathogens:
P.g. Tannerella forsythia Treponema denticola A.a. Prevotella Intermedia
103
Red Complex:
P.g. T.f. T.d.
104
What oral manifestation of HIV usually presents at the lateral border of the tongue, is corrugated, and may appear shaggy?
Hairy leukoplakia ***doesn't wipe off *take biopsy
105
Aside from Hairy Leukoplakia and Oral Candidiasis, name 3 oral manifestations of HIV:
Bacillary angiomatosis (red, purple, blue soft lesion) Kaposi sarcoma (HHV8) Hyperpigmentation (typically from meds)
106
T/F | NUS - necrotizing ulcerative stomatitis, is common periodontal disease in AIDS pts
True
107
NUS, NUG, NUP, and _______ are Perio diseases in HIV pts.
Linear Gingival Erythema * diffuse gingivitis * Fiery red **doesn't reflect CD4 count
108
5 Oral signs/symptoms of Diabetes:
Xerostomia Burning Mouth Periodontal abscesses Dental caries Candidiasis
109
T/F Diabetes pts have impaired wound healing, increased plaque from xerostomia, abscesses, altered PMN chemotaxis, and increased bone resorption.
True
110
Glycosylated Hb Assay (HbA1c) Normal: Moderate control: Needs improvement:
5-6% 6-7% >8% *each 1% change = 25-35 mg/dl glc
111
T/F | Proper diagnosis is the most important factor in treating PD
True
112
Primary bacteria associated with gingivitis is balance between G+ and G-
True
113
Tetracycline/Doxycycline is given in low doses to treat/regulat MMP
True *NOT as a replacement to Perio Treatment
114
Biological width =
2-3 mm
115
Allergic Gingival Enlargments are Plasma Cell associated
True *changing toothpastes, etc
116
4 Zones of NUG
Zone 1: Bacterial Zone 2: Neutrophil Zone 3: Necrotic Zone 4: Spirochete infiltration
117
Acute herpetic gingivostmatitis usually has primary infection early in life and has a viral shedding active phase of _____ days
12 days *only occurs on attached after reactivation
118
Primary herpetic gingivostmomatitis shows "balloning degeneration" including Acantholysis - which is separtation of the prickle cells of the stratum spinosum - then nuclear enlargement. Infected cells fuse, forming multinucleated cells. This leads to vesicle formation surrounded by zone rich in engorged blood vessels
True *diagnosed with Tzanck smear, serum Ab titer - ELISA or PCR
119
3 Systemic meds for Herpes:
Valcyclovir Vibaradine Acyclovir
120
3 Topical meds for Herpes:
Acyclovir Penciclovir Docosanol
121
What is the most important cause of Localized Marginal Recession?
Tooth position in arch