Neuro Never Ends Flashcards by MO ROUTH

Describe the histology/stuff of pilocytic astrocytoma

Cystic tumor of cerebellum 
Spindle Cells
Rosenthal Fibers 
Granular eosinophilic bodies 
*Kids

How well did you know this?

Not at all

Perfectly

Describe the histology/stuff glioblastoma multiforme

Deep structures
Crosses midline- butterfly
Pleomorphic astrocytes
*Necrosis/ microvasculature

How well did you know this?

Not at all

Perfectly

Describe the histology/stuff medulloblastoma

Primitive Neuroectoderm 
Homer Wright rosettes
Small round blue cells 
*Kids, posterior fossa
*Bad prognosis

How well did you know this?

Not at all

Perfectly

Describe the histology/stuff ependymoma

4th ventricle
kids
Pseudorosettes

How well did you know this?

Not at all

Perfectly

Describe the histology/stuff neuroblastoma

N-Myc
Extra Cranial
Kids

UA
homovanillic acid
and/or
vanillymandelic acid

How well did you know this?

Not at all

Perfectly

What is synaptophysin

Neuroendocrine or neuroectoderm cells

How well did you know this?

Not at all

Perfectly

Neoplasms of _____ origin stain + for GFAP

Glial origin= GFAP

Astrocytoma
Ependymoma
Oligodroglioma

How well did you know this?

Not at all

Perfectly

What are all the DSM 5 features of major depressive disorder

> 2 weeks

Need 5 or more of

*Depressed mood
*Loss of interest
Change in appetite/weight
Sleep problems
Psychomotor retardation/agitation
Low energy
Poor concentration
Worthlessness/ guilt
SI

How well did you know this?

Not at all

Perfectly

Crescent shaped bleed

Gradual Onset of s/s

Subdural hematoma

How well did you know this?

Not at all

Perfectly

This describes the congenital absence of Gyri

Lissencephaly

How well did you know this?

Not at all

Perfectly

Normal CSF content
Younge obese women
↑ ICP

Pseudotumor cerebri

How well did you know this?

Not at all

Perfectly

What are the characteristics of cocaine/ “upper” withdrawal

Depression
Fatigue
Hypersomnia
Hyperphagia
Vivid Dreams

How well did you know this?

Not at all

Perfectly

Hypoplasia/absence of cerebellar vermis

Dandy walker malformation
Cystic dilation of 4th ventricle
non communicating hydrocephalus

How well did you know this?

Not at all

Perfectly

Strongest risk for SI

1- previous SI attempt

also, 90% have diagnosable psych illness at time of death by SI

How well did you know this?

Not at all

Perfectly

What kind of drug is Thiopental

Barb
↑ Duration of Cl channel / Gaba

Has rapid onset/ rapid recovery (from redistribution) good for induction ANA, usually not maintenance

How well did you know this?

Not at all

Perfectly

How many words should a kid say at 2 years old

50-200

How well did you know this?

Not at all

Perfectly

Which Cranial Nerves exit at midbrain

3, 4

How well did you know this?

Not at all

Perfectly

Which cranial nerves exit at Pons

5-8

How well did you know this?

Not at all

Perfectly

Which CN exit at medulla

9, 10, 12

How well did you know this?

Not at all

Perfectly

Which CN exits at spine

CN 11

How well did you know this?

Not at all

Perfectly

Which CN exits the dorsal brain stem

CN 4 leaves the stem dorsally

How well did you know this?

Not at all

Perfectly

Which CN exits directly out of middle of pons

Trigeminal

How well did you know this?

Not at all

Perfectly

What is the major problem for patients recovering from subarachnoid hemorrhage

Vasospasm 4- 12 days after bleed is problematic

major cause of morbidity and mortality

How do you treat SAH vasospasm

Ca Channel Blocker - Nimodipine

Which antipsychotics has the most anti-cholinergic effects

Low potency FGAs

What does a tricyclic overdose look like

Anticholinergic particularly amitriptyline

What characterizes borderline personality

unstable relationships mood lability impulsive SI in context of interpersonal crisis

How does Ketamine work

blocks NMDA receptors

What receptor does PCP work on

NMDA antagonist

Symptoms of temporal arteritis

giant cell vasculitis HA--> Blindness Jaw Claudication Polymyalgia rheumatica

What do you call the inflammation of polymyositis

Endomysial

What do you call the inflammation of Guillain Barre

Endoneural

The _____ is the measure of potency for an inhaled anesthetic

Minimum Alveolar concentration

What is MAC

min alveolar concentration concentration when ana renders 50% of patients unresponsive

What are the 2 presentations of TMJ and why

muscle of mastication problem otologic problem mandibular trigeminal supplies jaw muscle and tensor tympani

What are the 3 ways urination is controlled

Sacral MIcturition center- S2-S4- bladder contraction Pontine Micturition center- coordinates voluntary voiding Cerebral cortex- can inhibit micturition center

What cell type is involved in CSF absorbtion

Arachnoid granules

Microscopy of creutzfeldt Jakob

multiple vacolues b/t neurons Abnoral prion protein rapid dementia and jerks

How does topical capsaicin work

defunctionalization of affernt pain fibers via ↑ TRPV1 channels, ↑ Ca--> dysfx of nociceptive fibers * depletion of substance p

Endorphin and dynorphins are

endogenous opiod peptides- activate mu

How does Cocain work

indirect sympathomimetic, inhibits reuptake of norepi, da, and 5ht

What is the staining for schwannomas

s-100

What brain tumor has psammoma bodies

Meningiomas

What is an optic glioma made of

astrocytes with rosenthal fibers

This treats refractory schizophrenia

clozapine | s/s= agranulocytosis

Compare binge eating and bulimia

binge eating: binges, but does not restrict/purge bulimia: binges then restricts

According to world, what is the difference b/t anorexia and bulimia

Weight Anorexics are thin bulimics are normal/overweight

What is the only recreational drug you should acs. w/ nystagmus

PCP

Minors wanting abortion

2/3 states require parental consent for abortion | 1/3 require parental notification

This is the most common cause of calcium kidney stone

Idiopathic hypercalciuria | serum is normocalcemia

Who will have a positive lepromin skin test

tuberculoid leprosy has + skin test due to Cd4 Th1 response Lepromatous leprosy has a weak th1 response, and - skin test

Which of these drugs can cross the BBB Physostigmine Neostigmine Edrophonium

Physostigmine Penetrates the BBB NEostimine does Not These are all anti-chole-esterase--> ↑ AcH

What causes 80% of malignancy hypercalcemia

PTHrP --> activates PTH receptor --> excessive bone resorbtion--> ↑ Ca lots of cancers can do this, very rare to elevate PTH itself in cancer

What is a common blood transfusion problem in IgA def

if you are IgA def, you will attack IgA in donor blood

What is the presentation of hypercalcemia

``` AMS muscle weakness constipation polyuria/polydipsia dehydration ```