Derm/Rheum Flashcards
When Will you see gluten associated DERM herpatiformis
40s and 50s
Rare in children
Where will you see DERM herpetiformis on body
Butt and extensors
What mutation is likely causing eczema
Filagrin
Asc w/ impairment of skins barrier function
Usually high ige present
A small blue tumor under the nail that hurts is from a cell type doing?
Thermo regulation (smooth m cell) of dermal glomus bodies
Ddx glomangioma
What is the lesser trelat sign
Sudden eruption of seborrheic keratosis that arise in response to internal malignancy
Nerve and fx of supraspinatous
Supra scapular
aBduction
Nerve and function of Infraspinatous
Supra scapular n
External rotation
Nerve and fx of teres minor
Axiallary
aDduction
External rotation
Subscapularis n and fx
Upper and lower subscap n
aDduction
Internal rotation
What cell type is active and targeted to treat gout
PMNs
NSAIDs decrease PMNs
Colchicine preferred if PUD
What is the most common rotator cuff injury
Tendon of supraspinatous
Pain with aBduction
Targetoid/Bullard rash diffusely after genital lesions might be
Erythema multiforme
Asc with HSV
Hyperkeratotic scaly plaque of the face is what, and leads to what
Actinic keratosis
Leads to squamous cell carcinoma
How will a basal cell ca look
Pearly papules with central depression or ulcer
Radical mastectomy with lymph removal leads to what outcomes
Chronic lymphedema first, which then progresses to development of angiosarcoma
The CREST stands for what
Calcinosis
Raynold
Esophogus dsymotility
Scleraldatcyly
Telengitecatsia
CREST autoantibody
Anti centromere
What is anti histone antibody
Drug induced lupus
Compare strawberry and cherry hemangioma
Strawberry - large, tounge people get em. Grows rapidly, regresses
Cherry- small, old people. Do not go away
Trendelnburg sign involves what nerve
Superior gluteal
Injury of this muscle may compress the sciatic nerve
Piriformis travels through the greater sciatic Foramen with the sciatic nerve
What does a frame shift usually result in
A shorter non fx protein
This lesion is found on eyelids and is comprised of foamy lipid laden macs
Xanthelasema
Often arises due to conditions that increase cholesterol
What cytokine is responsible for fibroblast migration and keloid formation
Transforming growth factor b
Tgf-b
What normal human cell had reverse transcriptase activity
Telomerase
Normally expressed in stem cells
Spaghetti and meat ball KOH prep
Tinea versicolor
Malassezia species
Hypo or hyper pigmented patches
Why does skeletal muscle not get effected by verapamil
Verapamil is a ca drug
Skeletal muscle does not require an influx of extra cellular ca
Smooth and cardiac muscle do relay on this
What is the sickle cell mutation
Point mutation
Glutamic acid replaced by valine on beta chain
If you peirce your ears conch, what nerve will feel it
Auricular branch of vagus
