Derm/Rheum Flashcards

1
Q

When Will you see gluten associated DERM herpatiformis

A

40s and 50s

Rare in children

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2
Q

Where will you see DERM herpetiformis on body

A

Butt and extensors

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3
Q

What mutation is likely causing eczema

A

Filagrin

Asc w/ impairment of skins barrier function

Usually high ige present

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4
Q

A small blue tumor under the nail that hurts is from a cell type doing?

A

Thermo regulation (smooth m cell) of dermal glomus bodies

Ddx glomangioma

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5
Q

What is the lesser trelat sign

A

Sudden eruption of seborrheic keratosis that arise in response to internal malignancy

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6
Q

Nerve and fx of supraspinatous

A

Supra scapular

aBduction

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7
Q

Nerve and function of Infraspinatous

A

Supra scapular n

External rotation

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8
Q

Nerve and fx of teres minor

A

Axiallary

aDduction

External rotation

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9
Q

Subscapularis n and fx

A

Upper and lower subscap n

aDduction

Internal rotation

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10
Q

What cell type is active and targeted to treat gout

A

PMNs

NSAIDs decrease PMNs
Colchicine preferred if PUD

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11
Q

What is the most common rotator cuff injury

A

Tendon of supraspinatous

Pain with aBduction

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12
Q

Targetoid/Bullard rash diffusely after genital lesions might be

A

Erythema multiforme

Asc with HSV

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13
Q

Hyperkeratotic scaly plaque of the face is what, and leads to what

A

Actinic keratosis

Leads to squamous cell carcinoma

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14
Q

How will a basal cell ca look

A

Pearly papules with central depression or ulcer

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15
Q

Radical mastectomy with lymph removal leads to what outcomes

A

Chronic lymphedema first, which then progresses to development of angiosarcoma

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16
Q

The CREST stands for what

A

Calcinosis

Raynold

Esophogus dsymotility

Scleraldatcyly

Telengitecatsia

17
Q

CREST autoantibody

A

Anti centromere

18
Q

What is anti histone antibody

A

Drug induced lupus

19
Q

Compare strawberry and cherry hemangioma

A

Strawberry - large, tounge people get em. Grows rapidly, regresses

Cherry- small, old people. Do not go away

20
Q

Trendelnburg sign involves what nerve

A

Superior gluteal

21
Q

Injury of this muscle may compress the sciatic nerve

A

Piriformis travels through the greater sciatic Foramen with the sciatic nerve

22
Q

What does a frame shift usually result in

A

A shorter non fx protein

23
Q

This lesion is found on eyelids and is comprised of foamy lipid laden macs

A

Xanthelasema

Often arises due to conditions that increase cholesterol

24
Q

What cytokine is responsible for fibroblast migration and keloid formation

A

Transforming growth factor b

Tgf-b

25
Q

What normal human cell had reverse transcriptase activity

A

Telomerase

Normally expressed in stem cells

26
Q

Spaghetti and meat ball KOH prep

Tinea versicolor

A

Malassezia species

Hypo or hyper pigmented patches

27
Q

Why does skeletal muscle not get effected by verapamil

A

Verapamil is a ca drug

Skeletal muscle does not require an influx of extra cellular ca

Smooth and cardiac muscle do relay on this

28
Q

What is the sickle cell mutation

A

Point mutation

Glutamic acid replaced by valine on beta chain

29
Q

If you peirce your ears conch, what nerve will feel it

A

Auricular branch of vagus