Derm/Rheum Flashcards

1
Q

When Will you see gluten associated DERM herpatiformis

A

40s and 50s

Rare in children

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2
Q

Where will you see DERM herpetiformis on body

A

Butt and extensors

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3
Q

What mutation is likely causing eczema

A

Filagrin

Asc w/ impairment of skins barrier function

Usually high ige present

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4
Q

A small blue tumor under the nail that hurts is from a cell type doing?

A

Thermo regulation (smooth m cell) of dermal glomus bodies

Ddx glomangioma

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5
Q

What is the lesser trelat sign

A

Sudden eruption of seborrheic keratosis that arise in response to internal malignancy

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6
Q

Nerve and fx of supraspinatous

A

Supra scapular

aBduction

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7
Q

Nerve and function of Infraspinatous

A

Supra scapular n

External rotation

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8
Q

Nerve and fx of teres minor

A

Axiallary

aDduction

External rotation

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9
Q

Subscapularis n and fx

A

Upper and lower subscap n

aDduction

Internal rotation

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10
Q

What cell type is active and targeted to treat gout

A

PMNs

NSAIDs decrease PMNs
Colchicine preferred if PUD

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11
Q

What is the most common rotator cuff injury

A

Tendon of supraspinatous

Pain with aBduction

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12
Q

Targetoid/Bullard rash diffusely after genital lesions might be

A

Erythema multiforme

Asc with HSV

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13
Q

Hyperkeratotic scaly plaque of the face is what, and leads to what

A

Actinic keratosis

Leads to squamous cell carcinoma

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14
Q

How will a basal cell ca look

A

Pearly papules with central depression or ulcer

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15
Q

Radical mastectomy with lymph removal leads to what outcomes

A

Chronic lymphedema first, which then progresses to development of angiosarcoma

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16
Q

The CREST stands for what

A

Calcinosis

Raynold

Esophogus dsymotility

Scleraldatcyly

Telengitecatsia

17
Q

CREST autoantibody

A

Anti centromere

18
Q

What is anti histone antibody

A

Drug induced lupus

19
Q

Compare strawberry and cherry hemangioma

A

Strawberry - large, tounge people get em. Grows rapidly, regresses

Cherry- small, old people. Do not go away

20
Q

Trendelnburg sign involves what nerve

A

Superior gluteal

21
Q

Injury of this muscle may compress the sciatic nerve

A

Piriformis travels through the greater sciatic Foramen with the sciatic nerve

22
Q

What does a frame shift usually result in

A

A shorter non fx protein

23
Q

This lesion is found on eyelids and is comprised of foamy lipid laden macs

A

Xanthelasema

Often arises due to conditions that increase cholesterol

24
Q

What cytokine is responsible for fibroblast migration and keloid formation

A

Transforming growth factor b

Tgf-b

25
What normal human cell had reverse transcriptase activity
Telomerase Normally expressed in stem cells
26
Spaghetti and meat ball KOH prep Tinea versicolor
Malassezia species Hypo or hyper pigmented patches
27
Why does skeletal muscle not get effected by verapamil
Verapamil is a ca drug Skeletal muscle does not require an influx of extra cellular ca Smooth and cardiac muscle do relay on this
28
What is the sickle cell mutation
Point mutation Glutamic acid replaced by valine on beta chain
29
If you peirce your ears conch, what nerve will feel it
Auricular branch of vagus