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What is raltegravir
integrase inhibitor vs HIV
How does vancomycin work
directly inhibits peptidoglycan synthesis
In ATN when do you have fluid overload
maintenance stage
↓ UA output
In ATN, what electrolyte problems do you have/ when
Happens in recovery phase
hypokalemia- most serious issue
Hypocalcemia
What muscle symptom can hypothyroid present with
↑ CK levels is common presenting symptom
myalgia
proximal muscle weakness
cramping
myoedema
What is a major side effect of protease inhibitors in HIV therapy
Hyperglycemia
drugs end in “Navir”
Where is most water in kidney absorbed
PCT
Can compress anterior cerebral artery.
Cingulate (subfalcine) herniation under
falx cerebri
Duret
hemorrhages. Usually fatal.
Downward transtentorial (central) herniation- caudal displacement of brainstem
uncal herniation
Uncus Compresses ipsilateral CN III (blown pupil, “down-and out” gaze)
Cerebellar tonsillar herniation into the foramen magnum outcome
coma and death if brainstem compressed
What is GLUT
carrier molecule to get glu into cell
Need to treat osteoporosis, DM, and htn, use this
thiazide
A dry bone marrow tap might be
hairy cell leukemia
middle aged peeps, bone marrow failure, splenomegally
Generally, how do fibrates work
↓ VLDL