MSK: Part 8 Flashcards

1
Q

Define fractures

A
  1. Soft tissue injury in which there is a break in the continuity of surface of substructure of the bone
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2
Q

Where do high energy injuries take place

A

Pelvic or femur fracture

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3
Q

What is the bone shaft in children called

A

Diaphysis

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4
Q

What is the peri-articular part of the bone called (ends of long bones)

A

Metaphysics

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5
Q

What is physics

A

Growth plate that has not fused

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6
Q

Blood supply of the epiphysis

A

Endoosteal and periosteal blood supply

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7
Q

Why is healing of bone better in children than adults

A

Children have an EXCELLENT PERIOSTEAL BLOOD SUPPLY so their rate of healing is MUCH HIGHER and is thus SIMPLE

More cancellous bone present in children which is softer - simple repair needed

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8
Q

Why are ligament damages in children very rare

A

They are extremely strong

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9
Q

Why do ligament injuries in children cause fractures

A

So strong - bone to bone

If they tear, they take the bone with it

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10
Q

Common fracture site in neonates

A

Humerus and clavicle due to fracture from birth

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11
Q

Common fracture site in infants

A

Radius

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12
Q

Common fracture site in children

A

Fibula, radius and femur

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13
Q

Common fracture site in adolescent

A

Tibia

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14
Q

What is an oblique fracture

A

Diagonal tear

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15
Q

What is a transverse fracture

A

Horizontal

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16
Q

What is a linear fracture

A

Vertical

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17
Q

What is a spiral fracture

A

Diagonal around the bone perimeter

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18
Q

What is a comminuted fracture

A

Section between bone is fragmented and separates the bone

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19
Q

What usually causes comminuted fracture

A

High energy impact

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20
Q

What causes a spiral fracture

A

Twisting injury

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21
Q

Where is an oblique fracture found

A

Ankle due to axial load injury

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22
Q

What age group is effected by greenstick fracture

A

SPECIFIC to children

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23
Q

What is a greenstick fracture

A

Unicortical fracture in which the bone bends and breaks due to thick periosteum

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24
Q

How easy is it to treat a greenstick fracture

A

EASILY because bone is not completely broken down

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25
What is the salter-Harris fracture classification
Classification for fractures involving the physics (growth plate) - higher the number the more damage and worse prognosis
26
What are the most common parts of the bone that get fractures in children
Epiphysis Metaphysis
27
Major complication of Salter-Harris fracture classification
GROWTH ARREST
28
How are fractures managed
1. Reduce fracture -> restore length, alignment and rotation -> immobilise (to allow healing) -> rehabilitate
29
How do most kids fractures heal
Non-operatively due to extremely quick healing as a result of their thick periosteum with excellent blood supply
30
What deformity will be remodelled if there is more than 2 years growth left in a bone
Angular deformities
31
What deformity will not be remodelled if there is more than 2 years growth left in a bone
Rotational deformity
32
How do we tell if a child has angular or rotational deformity
Regular X-rays to ensure no rotational/angular movement
33
Treatment for paediatric fractures
1. Internal operational fixation | 2. External fixation
34
What is Internal operational fixation
1. Plate, screws, intramedullary nails or K-wire
35
Complication of internal operational fixation
If nails or K-wire INVADE the physics (growth plate) then there will be growth arrest
36
When are external fixations done
Lots of soft tissue swellings and damage so don't want to open skin to reduce risk of infection and bad healing Ex-fix or Lizard flame
37
Complication of an open fracture
Infection
38
Complication of fractures in general
Neuromuscular compromise Malunion - bone heals with DEFORMITY Non-union - Failure of bone to heal Compartment syndrome
39
What is compartment syndrome
1. Painful condition in which the pressure within the fascia builds to dangerous levels usually caused by bleeding within the fascia
40
Where is compartment syndrome common
Tibia
41
What causes compartment syndrome
Cast (too tight) or post-op bleeding of fascia
42
How is compartment syndrome treated
Fasciotomy where fascia is removed
43
How do radiographs work
X-ray beam is directed through the body part under investigation and then into a plate Various tissues absorb different amounts of X-ray beams X-rays reach plate and are converted to light by phosphorescent effect Light is then digitally recorded The more X-ray radiation that reaches the detector, the darker the image becomes
44
What colour is bone on X-ray
White
45
What colour is soft tissue on x-ray
Light grey
46
What colour is fat on x ray
Dark grey
47
Cons of X-ray (non safety related)
Fractures take time to appear on X-ray Early arthritis and early infection do not show
48
When requesting a radiograph what do we need to ask for to get a full picture of the injury
TWO VIEWS of the body
49
How does a CT work
Radiation source is fired through patient and then what passes is detected Multiple slices of the body seen AXIAL
50
What people is CT dangerous for
Foetus and children are sensitive to radiation Pregnancies unless condition is life-threatening
51
How many days of background radiation is CT equivalent to
3 days
52
When is a CT useful
Assess ACUTE injuries when X-rays are inadequate Give greater information about known fractures Assess fracture healing and complications such as infection Look for loose bone fragments in joints Gives excellent detail of bone and joint pathology
53
When is an MRI preferred to CT in fractures
Soft tissue injuries
54
How does a Ultrasound scan work
HIGH FREQUENCY SOUND WAVES pass through soft tissues and reflected at tissue interfaces - good res Reflected waves or echoes are measured by probe
55
Difference between normal ultrasounds and MSK ultrasounds
Uses highest frequency, linear array probes for better res of small soft tissue structures
56
Why re ultrasounds safe
NO Radiation or magnetic field
57
What sound wave should not be used in foetal scanning
Power doppler
58
When is USS used
Tendon and ligament soft tissue injuries and anatomy assessment for joints and synovial abnormalities, effusions and cortical erosions Guide biopsies and fluid drainage
59
How does an MRI function
1. Patient is placed in a powerful magnetic field 2. 30,000 x stronger than the earth's magnetic field 3. Scanner is narrow and often induces claustrophobia
60
How does an MRI work
1. T1 energy: released from spinning proton to surrounding lattice 2. T2 energy relaxation: Released from spinning proton to adjacent spinning protons
61
Pathology of MRI
1. Abnormal tissues contain more water than normal tissues diseases appear DARKER on T1 and brighter on T2
62
Why are MRIs safe
No harmful effects from magnetic fields
63
When is MRI contraindicated
Patients with electronic implants and metallic heart valves, neurosurgical clips, metallic foreign objects in the eye
64
Consequence of metallic foreign objects in the eye if MRI is used
Transient tissue warming and visual disturbances
65
Why should MRI be avoided in pregnancy
uncertain foetal safety
66
Why is MRI used to assess bone fractures
Soft tissue pathology around bones and joints Information on characteristics of tissue and pathology Useful early in disease when plain radiographs may be normal
67
Con of MRI
Early diseases can't be seen
68
When is Aldendronate given
Osteoporosis Hypercalcaemia of malignancy Myeloma and breast cancer bone metastasis as it reduces need for radiotherapy or surgery Paget's disease to reduce bone turnover and pain
69
How do bisphosphonates function
Inhibit osteoclasts and promoting apoptosis
70
Adverse effects of bisphosphonates
1. Oesophagitis (orally) 2. Hypophosphataemia 3. Jaw osteonecrosis
71
When should bisphosphonates be avoided
1. Severe renal impairment 2. Hypocalcaemia 3. Upper GI disorders
72
What compounds contraindicate bisphosphates
Absorption reduced by calcium products (antacids and iron salts)
73
When is calcium and vit D given
1. Osteoporosis 2. CKD to stop secondary hyperparathyroidism and renal osteodystrophy 3. Calcium used in severe hyperkalaemia in arrhythmias 4. Symptomatic hypocalcaemia 5. Rickets and osteomalacia (VIT D)
74
What controls calcium homeostasis
1. Parathyroid hormone and Vit D which increases serum calcium levels and bone mineralisation 2. Calcitonin which reduces serum calcium levels Restoring positive calcium balance reduces the rate of bone loss and prevents fractures
75
Adverse effects of calcium and vit D oral medications
1. Dyspepsia and constipation 2. DO NOT USE in hypercalcaemia 3. Calicum reduces absorption of iron, bisphosphonates and tetracycline antidepressants
76
Example of Xanthine oxidase inhibitors
ALLOPURINOL
77
Is allopurinol a chemotherapy drug
Yes - stops hyperuricaemia and tumour lysis syndrome
78
How does allopurinol effect the plasma uric acid concentration
Lowers it
79
Contraindications for xanthine oxidase inhibitor
1. SKIN RASH 2. not with ACUTE GOUT ATTACKS - worsens these 3. recurrent skin rash already on the drug 4. IF patient is on azathioprine 5. Amoxicillin, ACEI or thiazides increase hypersensitivity risk
80
Why is xanthine oxidase contraindicated with azathioprine
Requires xanthine oxidase for metabolism so allopurinol may increase their activity
81
name an anti-gout agent
Colchicine
82
Mechanism of colchicine
Inhibits neutrophil motility and activity which leads to a net anti-inflammatory effect which is useful in acute attacks
83
Contraindications for colchicine
1. GI disturbances 2. fatigue due to anaemia 3. Renal impairment 4. Peripheral neuropathy due to peripheral nerve damage 5. Toxicity enhanced when using statins
84
How does methotrexate function
Inhibits dihydrofolate educates which converts dietary folic acid to FH4 (tetrahydrofolate) which is required for DNA and protein synthesis
85
What is FH4 needed for
Lack prevents cellular respiration Anti-inflammatory and immunosuppressive effects mediated by IL-6 and TNF-alpha
86
Contraindications of methotrexate
1. Sore mouth, GI upset, bone marrow suppression 2. Hepatic cirrhosis and pulmonary fibrosis 3. Severe renal impairment and abnormal liver function
87
What is Dupytren's contracture
1. Where fingers become permanently bent in a flexed position
88
What is hypothenar hammer syndrome
Occlusion of the ulnar artery and superficial palmar arch
89
What is Cozen's test
TEST FOR LATERAL EPICONDYLITIS: Rested wrist extension causing pain in lateral epicondyle - extensor carpi radialis causes this
90
What is repetitive strain disorder's differential diagnosis
Tenosynovitis and epicondylitis