Epithelia Flashcards
What are the 4 tissues types?
connective, muscle, epithelium, nervous
Where is epithelial tissue found?
Lining all body surfaces - epidermis, all internal tubes and cavities (digestive, cardiovascular, respiratory systems)
How are all epithelia arranged?
Continuous sheets of tightly bound cells.
Main functions of epithelial tissues
Barrier function - boundary between different environments, regulate movement of substances, protect against microbial invasion.
What is the name of the surface adjacent to the lumen/external surface?
Apical surface
What is the name of the surface adjacent to the interior surface?
Basal surface
Which surface of epithelial cells are adhered to each other?
Lateral surfaces
What feature of epithelial cells allows the unidirectional transport of molecules?
Epithelial cells are polarised
What is the importance of tight junctions between epithelial cells?
Creates an impermeable seal between adjacent cells which prevents water passage
What are the names of the junctions that anchor adjacent epithelial cells together? Allowing epithelial tissues to stretch and maintain contact
Desmosomes
Function of epithelial tissue in the skin and oral cavity
Physical protection from mechanical abrasion
Function of epithelial tissues in the lungs and blood capillaries
diffusion of gases, nutrients and waste between blood and surroundings
Function of epithelial tissues in the gastrointestinal tract / renal tubules
Absorption of nutrients
Function of epithelial tissues in glands and ducts
Secretion of sweat, mucus, enzymes, hormones
How are epithelial tissues classified?
3 ways - cell shape, number of cell layers, apical specialisation
What are the possible shapes of epithelial cells?
Squamous, cuboidal, columnar
Classification of epithelial tissues based on number of layers
simple, stratified, pseudostratified
How can epithelial tissue be pseudostratified?
When columnar cells are arranged in a single layer but appear to be stratified due to the varying location of the nuclei
What are the possible apical specialisations of epithelial tissue?
Microvilli, cilia, keratin
Function of microvilli
Increase apical SA for absorption
Function of cilia
Movement of particulate matter
Function of keratin
strong protective apical layer
Function of simple squamous epithelia
lines surfaces involved in passive diffusion
Location of simple squamous epithelia
Alveoli and endothelium (capillaries)
Function of simple cuboidal epithelia
lines small ducts and tubules involved in secretion (glandular epithelium) or absorption
Location of simple cuboidal epithelia
Renal tubules, small ducts of salivary glands
Function of simple columnar epithelia
Lines absorptive surfaces
Location of simple columnar epithelia
small intestine (epithelia has microvilli)
Function of ciliated simple columnar epithelia
Ciliary action facilitates transport of ovum from ovary to uterus
Location of ciliated simple columnar epithelia
female reproductive tract
Function of ciliated pseudostratified columnar epithelia
ciliary action propels mucus containing trapped particles towards pharynx
Location of ciliated pseudostratified columnar epithelia
Airways of respiratory system (respiratory epithelium)
What cells are modified to form goblet cells?
Columnar epithelial cells
Function of goblet cells
synthesise and secrete mucus
Location of goblet cells
scattered throughout simple columnar epithelia in the respiratory and gastrointestinal system.
Function of stratified cuboidal epithelia
secretory
Location of stratified cuboidal epithelia
some secretory ducts and glands. rare
function of stratified columnar epithelia
secretory and protective
Location of stratified columnar epithelia
male urethra and lining some glands. rare
Function of stratified squamous epithelia
protection from mechanical abrasion
location of stratified squamous epithelia
oral cavity, epidermis
How is stratified squamous epithelia formed
cells mature from continuously dividing cells in the basal layer and gradually migrate to the surface where they shed as anucleate squames
what are the apical specialisations of stratified squamous epithelia
non-keratinised or keratinised
Function of keratin
enhances resistance to physical stress
How is keratin formed?
keratin filaments are accumulated by epithelial cells as they mature, which forms a tough, non-living surface layer
Function of transitional epithelium
allows for stretch and expansion
location of transitional epithelium
only in bladder
How does oral squamous cell carcinoma occur?
Uncontrolled proliferation of dysplastic (abnormal) epithelial cells which destroy and invade adjacent tissues