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gi - 2 > Agents for IBD > Flashcards

Agents for IBD Flashcards

1
Q

IBD

A

Inflammatory Bowel Disease

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2
Q

2 types of IBD?

A

Ulcerative Colitis

Crohn’s Disease

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3
Q

2 types of IBD?

A

Ulcerative Colitis

Crohn’s Disease

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4
Q

5 agent classes to treat Ulcerative Colitis?

A
  1. 5-ASA
  2. JAK (-)
  3. IL12/23 (-)
  4. TNF-alpha (-)
  5. Alpha-4 integrin (-)
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5
Q

3 agent classes to treat Crohn’s Disease?

A
  1. IL-12/23 (-)
  2. TNF-alpha (-)
  3. Alpha-4 integrin (-)
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6
Q

List the 5-ASA class members

A

Sulfsalazine
Mesalamine
Olsalazine
Balsalazide

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7
Q

List the 5-ASA class members

A

Sulfsalazine
Mesalamine
Olsalazine
Balsalazide

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8
Q

List the 5-ASA class members

A

Sulfsalazine
Mesalamine
Olsalazine
Balsalazide

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9
Q

List the JAK inhibitor

A

Tofacitinib

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10
Q

List the JAK inhibitor

A

Tofacitinib

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11
Q

List the JAK inhibitor

A

Tofacitinib

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12
Q

List the IL-12/23 inhibitor

A

Ustekinumab

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13
Q

List the IL-12/23 inhibitor

A

Ustekinumab

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14
Q

List the TNF-alpha inhibitors that treat both ulcerative colitis and crohn’s disease

A

Adalimumab

Infliximab

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15
Q

List the TNF-alpha inhibitors that treat both ulcerative colitis and crohn’s disease

A

Adalimumab

Infliximab

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16
Q

List the TNF-alpha inhibitor that can only treat ulcerative colitis

A

Golimumab

17
Q

List the TNF-alpha inhibitor that can only treat ulcerative colitis

A

Golimumab

18
Q

List the TNF-alpha inhibitor that can only treat crohn’s disease

A

Certolizumab

19
Q

List the TNF-alpha inhibitor that can only treat crohn’s disease

A

Certolizumab

20
Q

List the Alpha-4 integrin inhibitor that can treat both ulcerative colitis and crohn’s disease

A

Vedolizumab

21
Q

List the Alpha-4 integrin inhibitor that can treat both ulcerative colitis and crohn’s disease

A

Vedolizumab

22
Q

List the Alpha-4 integrin inhibitor that can only treat crohn’s disease

A

Natalizumab

23
Q

List the Alpha-4 integrin inhibitor that can only treat crohn’s disease

A

Natalizumab

24
Q

When should you use TNF-alpha inhibitors?

A

After an inadequate response to conventional or immunosuppressant therapy

25
Q

When should you use IL-12/23 inhibitors?

A

After an inadequate response to conventional, immunosuppressant or TNF-alpha therapy

26
Q

When should you use Alpha-4 integrin inhibitors?

A

After an inadequate response to conventional, immunosuppressant or TNF-alpha therapy

27
Q

What can be used for uncontrolled, acute or severe ulcerative colitis/crohn’s disease?

A

Glucocorticosteroids

28
Q

What 4 drugs can treat both Ulcerative Colitis and Crohn’s Disease?

A

Ustekinumab
Adalimumab
Infliximab
Vedolizumab

29
Q

What 4 drugs can treat both Ulcerative Colitis and Crohn’s Disease?

A

Ustekinumab
Adalimumab
Infliximab
Vedolizumab

30
Q

What 4 drugs can treat both Ulcerative Colitis and Crohn’s Disease?

A

Ustekinumab
Adalimumab
Infliximab
Vedolizumab

gi - 2 (61 decks)

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