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GI - 2 > Acute Hepatitis > Flashcards

Acute Hepatitis Flashcards

1
Q

Hepatitis

A

Liver inflammation

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2
Q

Most common etiologies for Acute Hepatitis?

A

Viral infection

Medications

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3
Q

Most common symptoms for Acute Hepatitis?

A

RUQ pain and hepatomegaly
N/V and Jaundice
Dark urine and Acholic stools

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4
Q

What is Acute Fulminant Liver Failure?

A

Massive hepatic necrosis with impaired consciousness within 8 weeks of onset of illness

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5
Q

What is the #1 cause of Acute Fulminant Liver Failure?

A

Acetaminophen overdose (APAP)

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6
Q

Sign/Symptoms of Acute Fulminant Liver Failure?

A

Rapidly SHRINKING liver
Confusion
Edema, Jaundice, pruritus, N/V

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7
Q

Symptoms of Acute Fulminant Liver Failure?

A

Rapidly SHRINKING liver
Confusion
Edema, Jaundice, pruritus, N/V

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8
Q

Describe the progression of the labs with Acute Fulminant Liver Failure as the liver fails

A
  • ELEVATED AST/ALT
  • ELEVATED bilirubin and prolonged PT/INR
  • DECREASED AST/ALT
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9
Q

If Acetaminophen causes Acute Fulminant Liver Failure, above what number will the AST/ALT likely be?

A

> 5000

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10
Q

2 possible complications of Acute Fulminant Liver Failure?

A
  • Cerebral/brainstem compression

- Sepsis and multi-organ failure

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11
Q

What is the treatment for Acetaminophen overdose?

A

N-Acetylcysteine

Liver transplant

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12
Q

What Nomogram should be used to find out Acetaminophen level?

A

Rumak - Matthew

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13
Q

Viral Hepatitis A

A

RNA virus
Fecal-oral spread
ACUTE

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14
Q

Viral Hepatitis A is more severe in ____

A

Adults

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15
Q

Is there a vaccine available for Hepatitis A?

A

YES

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16
Q

Labs with Hepatitis A?

A

Increased bilirubin and alkaline phosphatase

Increased AST/ALT

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17
Q

Treatment for Hepatitis A?

A

Supportive; self-limited

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18
Q

Viral Hepatitis B

A

DNA virus
Blood/sex/mother to baby spread
Usually ACUTE (some chronic)

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19
Q

What extra symptom may be seen with Hepatitis B?

A

Cutaneous Polyarteritis Nodosa

20
Q

Cutaneous Polyarteritis Nodosa is seen with?

A

Hepatitis B

21
Q

Labs with Hepatitis B?

A

Increased AST/ALT

Prolonged PT/INR – bleeding risk

22
Q

Hepatitis B has a window period. What is that?

A

Time between when the HBsAg has disappeared and the HBsAb has appeared
– weeks to months

23
Q

Hepatitis B has a window period. What is that?

A

Time between when the HBsAg has disappeared and the HBsAb has appeared
– weeks to months

24
Q

During the Window period with Hepatitis B, the patient is considered to have?

A

ACUTE hepatitis B!

25
During the Window period with Hepatitis B, the patient has Acute Hepatitis B, what test will be (+)?
IgM
26
Is there a vaccine available for Hepatitis B?
YES
27
Viral Hepatitis D requires?
Hepatitis B infection!!
28
What will be (+) with Hepatitis D?
HDV RNA PCR
29
How do you protect against Hepatitis D?
Vaccinate against Hepatitis B
30
Hepatitis D enhances severity of?
Hepatitis B infection
31
Viral Hepatitis C
RNA Blood/needle spread CHRONIC
32
Symptoms of Hepatitis C?
Mild and Asymptomatic
33
Labs with Hepatitis C?
FLUCTUATING AST/ALT
34
Fluctuating AST/ALT is seen with?
Hepatitis C
35
(+) HCV RNA or Ab can diagnose Hepatitis C. If there are Anti-HCV in the serum but NO RNA, what does that mean?
Prior infection
36
Is there a vaccine available for Hepatitis C?
NO
37
Complications of Hepatitis C?
Cirrhosis Mixed Cryoglobulinemia Hepatocellular Carcinoma
38
What is the recommended prevention for Hepatitis C?
- Screen baby boomers and those over 18, along with blood products - Do not share toothbrush or razor if infected
39
Viral Hepatitis E
RNA Fecal-oral (swine) spread ACUTE or CHRONIC if immunocompromised
40
When will Viral Hepatitis E be Chronic?
In immunocompromised patients
41
When will Hepatitis E progress from Chronic to Cirrhosis?
In transplant patients on Tacrolimus
42
When can Fulminant Hepatitis E occur?
In pregnant patients
43
Is there a vaccine available for Hepatitis E?
NO
44
In what Hepatitis's is there vaccines available?
A and B
45
Symptoms of Acute Hepatitis?
RUQ pain, Hepatomegaly Jaundice and N/V Dark urine and Acholic stool

GI - 2 (61 decks)

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