Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GI - 2 > Agents for Constipation > Flashcards

Agents for Constipation Flashcards

1
Q

What are 4 classes of drugs to treat Constipation?

A
  1. Peripheral Opioid Antagonists
  2. Guanylate Cyclase-C Agonists
  3. Cl- 2 Channel Activator
  4. Serotonin 4 Partial Agonists
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are 4 classes of drugs to treat Constipation?

A
  1. Peripheral Opioid Antagonists
  2. Guanylate Cyclase-C Agonists
  3. Cl- 2 Channel Activator
  4. Serotonin 4 Partial Agonists
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the Peripheral Opioid Antagonist Agents?

A

Methylnaltrexone
Naloxegol
Alvimopan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the Peripheral Opioid Antagonist Agents?

A

Methylnaltrexone
Naloxegol
Alvimopan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MOA for the Peripheral Opioid Antagonist Agents?

A

Peripherally acting mu receptor antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What receptor do the Peripheral Opioid Antagonist Agents block?

A

mu

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Peripheral Opioid Antagonists are indicated for?

A

Opioid Induced Constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is Alvimopan only used to treat?

A

Prevent post-op Ileus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What Peripheral Opioid Antagonist is used to prevent post-op Ileus?

A

Alvimopan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Those on Alvimopan are at risk for?

A

MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the Guanylate Cyclase-C Agonist?

A

Linaclotide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the Guanylate Cyclase-C Agonist?

A

Linaclotide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is Linaclotide indicated for?

A

IBS-C and Chronic Idiopathic Constipation

irritable bowel syndrome - constipation subtype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drug/class is indicated only for IBS-C and Chronic Idiopathic constipation?

A

Linaclotide/Guanylate Cyclase-C Agonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the Chloride 2 Channel Activator?

A

Lubiprostone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the Chloride 2 Channel Activator?

A

Lubiprostone

17
Q

What drug to treat Constipation is a Prostaglandin E1 Derivative?

A

Lubiprostone

cl- 2 channel activator

18
Q

MOA for Lubiprostone?

A

Activates Cl- 2 channels to increase fluid secretion

19
Q

Lubiprostone can be used to treat?

A

Most of the constipation types

20
Q

What is the Serotonin type 4 Partial Agonist?

A

Tegaserod

21
Q

What is the Serotonin type 4 Partial Agonist?

A

Tegaserod

22
Q

What is Tegaserod indicated for?

A

IBS-C for women > 65

23
Q

What is Tegaserod indicated for?

A

IBS-C for women > 65

24
Q

MOA for Tegaserod?

A

Partial agonist for serotonin type 4 receptors

25
Q

Most of the drugs used to treat constipation are going to do what?

A

Increase fluid secretion and peristalsis

26
Q

This drug can prevent post-op ileus

A

Alvimopan

27
Q

This drug can treat IBS-C in women older than 65

A

Tegaserod

28
Q

This drug is a derivative of prostaglandin E1 and activates chloride 2 channels

A

Lubiprostone

29
Q

This drug is indicated to treat opioid-induced, IBS-C and Chronic idiopathic constipation?

A

Lubiprostone

30
Q

This drug is indicated to treat IBS-C and Chronic idiopathic constipation?

A

Linaclotide

GI - 2 (61 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions