18-6 Flashcards
Choledochal cyst
Congenital dilation of common bile duct
Congenital dilation of common bile duct
Choledochal cyst
When/who do Choledochal cysts usually present in?
Female children
Symptoms of Choledochal cysts?
Jaundice and abdominal pain
Symptoms of Choledochal cysts?
Jaundice and abdominal pain
Kids with Choledochal cysts are at an increased risk to develop what conditions?
Stone formation
Stenosis
Pancreatitis
Obstructive biliary issues
What 3 things fall under the Fibropolycystic Disease category?
Von Meyenburg Complexes
Caroli Disease/Syndrome
Congenital Hepatic Fibrosis
What 3 things fall under the Fibropolycystic Disease category?
Von Meyenburg Complexes
Caroli Disease/Syndrome
Congenital Hepatic Fibrosis
Von Meyenburg Complexes
Bile duct hamartomas
Bile duct hamartomas
Von Meyenburg complexes
Caroli Disease
Multifocal cystic dilation of large intrahepatic bile ducts
Multifocal cystic dilation of large intrahepatic bile ducts
Caroli Disease
Caroli Syndrome
Multifocal cystic dilation of large intrahepatic bile ducts + Congenital hepatic fibrosis
Multifocal cystic dilation of large intrahepatic bile ducts + congenital hepatic fibrosis
Caroli Syndrome
Congenital hepatic fibrosis
Bands of collagenous tissue that form septa and divide the liver into islands
Bands of collagenous tissue that form septa and divide the liver into islands
Congenital hepatic fibrosis
Congenital hepatic fibrosis includes _____ shaped bile ducts imbedded in the fibrosis
Abnormally shaped bile ducts
Those with Congenital hepatic fibrosis are at an increased risk for?
Portal HTN and bleeding varices
Fibropolycystic Disease
Congenital malformations of the biliary tree
- Von Meyenburg Complexes
- Caroli Disease/Syndrome
- Congenital Hepatic Fibrosis
What causes Fibropolycystic Disease?
Ductal plate malformations due to the persistence of fetal periportal ductal plates
What is associated with Fibropolycystic Disease?
Renal polycystic disease
– Increased risk for cholangiocarcinoma
2 causes of Impaired blood flow into the liver?
- Hepatic A. compromise
2. Portal vein obstruction
Signs of Hepatic A. compromise?
Pale or hemorrhagic infarct of the liver
Common causes of Hepatic A. compromise?
Neoplasia, polyarteritis nodosa, sepsis
Symptoms of Portal vein obstruction?
Abdominal pain, portal HTN with ruptured esophageal varices
Symptoms of Portal vein obstruction?
Abdominal pain, portal HTN with ruptured esophageal varices
What can cause extrahepatic portal vein obstruction?
Idiopathic
Umbilical vein catheterization
Hypercoagulable states
What usually causes small branch portal vein obstruction?
Schistosomiasis - parasites laying eggs that cause obstruction
Schistosomiasis (parasites laying eggs) can cause?
Small branch portal vein obstruction
Signs of small branch portal vein obstruction?
NONcirrhotic portal HTN
NONcirhortic portal HTN
Small branch portal vein obstruction
Most common cause of impaired blood flow through the liver?
CIRRHOSIS
Most common cause of impaired blood flow through the liver?
CIRRHOSIS
Besides cirrhosis, what is another condition where blood flow is impaired through the liver?
Peliosis Hepatitis
Peliosis Hepatitis
Sinusoidal dilation where EFFLUX of hepatic blood is impeded
Peliosis Hepatitis
Sinusoidal dilation where EFFLUX of hepatic blood is impeded
What will the liver contain with Peliosis Hepatitis?
Blood-filled cystic spaces
– sinusoidal dilation where EFFLUX of hepatic blood is impeded
What conditions may cause Peliosis hepatitis?
AIDs - bartonella species
Cancer
TB
Sex hormone administration
2 causes of Hepatic venous outflow obstruction?
Hepatic vein thrombosis
Sinusoidal obstruction syndrome
Hepatic vein thrombosis =
Budd-Chiari syndrome
Symptoms of Hepatic Vein Thrombosis (budd-chiari syndrome)?
Abdominal pain, ascites, hepatomegaly
Symptoms of Hepatic Vein Thrombosis (budd-chiari syndrome)?
Abdominal pain, ascites, hepatomegaly
In what 2 settings can Sinusoidal obstruction syndrome occur?
- Following allogenic HSC transplant
2. Cancer pts on chemotherapy
Symptoms of Sinusoidal obstruction syndrome?
Ascites, hepatomegaly, weight gain and jaundice
Symptoms of Sinusoidal obstruction syndrome?
Ascites, hepatomegaly, weight gain and jaundice
What will a doppler US see with Sinusoidal obstruction syndrome?
Reversed/attenuated hepatic venous flow
Preeclampsia
Maternal HTN, proteinuria, peripheral edema and coagulation abnormalties
Preeclampsia
Maternal HTN, proteinuria, peripheral edema and coagulation abnormalities
Signs of Preeclampsia?
HELLP
- Hemolysis
- Elevated Liver enzymes
- Low Platelets
Signs of Preeclampsia?
HELLP
- Hemolysis
- Elevated Liver enzymes
- LOW platelets
Eclampsia
Maternal HTN, proteinuria, peripheral edema, coagulation abnormalities +
Hyperreflexia and convulsions
Eclampsia
Maternal HTN, proteinuria, peripheral edema, coagulation abnormalities +
Hyperreflexia and convulsions