17-7 -- IBS/IBD Flashcards
IBS
Irritable Bowel Syndrome
Symptoms of IBS?
Relapsing abdominal pain, bloating and changes in bowel habits
Relapsing abdominal pain, bloating and changes in bowel habits
IBS
Microscopic evaluations of IBS?
NORMAL
Most common people affected by IBS/IBD
Females 20-40 in high income countries
Ashkenazi Jews
For IBS, there is interplay between stressors, diet, abnormal GI motility and increased enteric sensory responses. What are 2 possible etiologies for IBS?
Excessive bile acid = IBS-D
Defective brain-gut signaling axis
For IBS, there is interplay between stressors, diet, abnormal GI motility and increased enteric sensory responses. What are 2 possible etiologies for IBS?
Excessive bile acid = IBS-D
Defective brain-gut signaling axis
2 types of IBD?
Ulcerative Colitis
Crohn Disease
Inappropriate immune activation against intestinal microbiota is seen with?
IBD
What 2 food changes are thought to increase IBD?
Increased food hygiene and preservatives
Crohn Disease - location
Ileum and Colon
= skip lesions
Ulcerative Colitis - location
Rectum and continuous colon involvement
Crohn Disease is patchy and often termed ___ lesions
Skip lesions
- ileum and colon
Crohn Disease has ____ inflammation
Transmural
Ulcerative Colitis has _____ inflammation
Mucosal
Something unique to Crohn Disease?
Creeping fat
= fat extends over serosa
Something unique to Ulcerative Colitis?
Pseudopolyps
= bulging mucosa
Ulcers may present with both types of IBD. Describe the differences in them.
Crohn - DEEP ulcers
Ulcerative Colitis - SUPERFICIAL
Marked Fibrosis and Serositis with possible fistulas occurs with what IBD type?
Crohn Disease
Crohn Disease bowel anatomical changes?
THICK walls with possible strictures present
What does the Mucosa look like in Ulcerative Colitis?
Red, granular with broad ulcers