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GI - 2 > 17-7 -- IBS/IBD > Flashcards

17-7 -- IBS/IBD Flashcards

1
Q

IBS

A

Irritable Bowel Syndrome

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2
Q

Symptoms of IBS?

A

Relapsing abdominal pain, bloating and changes in bowel habits

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3
Q

Relapsing abdominal pain, bloating and changes in bowel habits

A

IBS

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4
Q

Microscopic evaluations of IBS?

A

NORMAL

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5
Q

Most common people affected by IBS/IBD

A

Females 20-40 in high income countries

Ashkenazi Jews

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6
Q

For IBS, there is interplay between stressors, diet, abnormal GI motility and increased enteric sensory responses. What are 2 possible etiologies for IBS?

A

Excessive bile acid = IBS-D

Defective brain-gut signaling axis

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7
Q

For IBS, there is interplay between stressors, diet, abnormal GI motility and increased enteric sensory responses. What are 2 possible etiologies for IBS?

A

Excessive bile acid = IBS-D

Defective brain-gut signaling axis

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8
Q

2 types of IBD?

A

Ulcerative Colitis

Crohn Disease

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9
Q

Inappropriate immune activation against intestinal microbiota is seen with?

A

IBD

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10
Q

What 2 food changes are thought to increase IBD?

A

Increased food hygiene and preservatives

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11
Q

Crohn Disease - location

A

Ileum and Colon

= skip lesions

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12
Q

Ulcerative Colitis - location

A

Rectum and continuous colon involvement

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13
Q

Crohn Disease is patchy and often termed ___ lesions

A

Skip lesions

- ileum and colon

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14
Q

Crohn Disease has ____ inflammation

A

Transmural

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15
Q

Ulcerative Colitis has _____ inflammation

A

Mucosal

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16
Q

Something unique to Crohn Disease?

A

Creeping fat

= fat extends over serosa

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17
Q

Something unique to Ulcerative Colitis?

A

Pseudopolyps

= bulging mucosa

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18
Q

Ulcers may present with both types of IBD. Describe the differences in them.

A

Crohn - DEEP ulcers

Ulcerative Colitis - SUPERFICIAL

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19
Q

Marked Fibrosis and Serositis with possible fistulas occurs with what IBD type?

A

Crohn Disease

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20
Q

Crohn Disease bowel anatomical changes?

A

THICK walls with possible strictures present

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21
Q

What does the Mucosa look like in Ulcerative Colitis?

A

Red, granular with broad ulcers

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22
Q

If the Pseudopolyp tips fuse with Ulcerative Colitis, what does that create?

A

Mucosal bridges

23
Q

What polymorphism may be present in some cases of Crohn Disease?

24
Q

What is the earliest lesion with Crohn Disease?

A

Aphthous ulcers

25
Q

The earliest lesion with Crohn Disease progresses how?

A

Aphthous ulcers coalesce to form an elongated, serpentine ulcer running along the axis of the bowel

26
Q

Crohn Disease often has a _____ appearance

A

Cobblestone

27
Q

Crohn Disease and ulcerative Colitis - mucosal changes

A

Crohn - edema and loss of mucosal folds

Ulcerative Colitis - Mucosal atrophy

28
Q

Iron deficient anemia, along with malabsorption and hypoalbuminemia can present with?

A

Crohn Disease

29
Q

Severe initial attack is seen with which IBD?

A

Ulcerative colitis

30
Q

Both IBD have intermittent diarrhea, abdominal pain, RLQ pain. What is more severe and seen with Ulcerative Colitis?

A

Bloody diarrhea attacks with stringy mucoid material

Cramps relieved by defection

31
Q

2 other causes of Chronic Colitis?

A

Diversion Colitis

Microscopic Colitis

32
Q

2 other causes of Chronic Colitis?

A

Diversion Colitis

Microscopic Colitis

33
Q

Describe how Diversion Colitis arises

A

Some GI disorders require a creation of an ostomy (blind distal segment of colon) from which fecal flow is diverted
– Colitis can develop in diverted segment

34
Q

Describe how Diversion Colitis arises?

A

Some GI disorders require a creation of an ostomy (blind distal segment of colon) from which fecal flow is diverted
– Colitis can develop in diverted segment

35
Q

Main sign of Diversion Colitis?

A

Numerous Mucosal Lymphoid Follicles

36
Q

Numerous mucosal lymphoid follicles could indicate?

A

Diversion Colitis

37
Q

2 types of Microscopic Colitis?

A

Collagenous Colitis

Lymphocytic Colitis

38
Q

Collagenous Colitis

A

Watery diarrhea without weight loss in middle aged women

39
Q

Water diarrhea without weight loss in middle aged women

A

Collagenous Colitis

Type of Microscopic Colitis

40
Q

Lymphocytic Colitis

A

Watery diarrhea without weight loss in autoimmune/celiac disease

41
Q

Watery diarrhea without weight loss in autoimmune/celiac disease

A

Lymphocytic Colitis

Type of Microscopic Colitis

42
Q

Graft Vs. Host Disease occurs following?

A

HSC transplant

43
Q

What are destroyed with Graft Vs. Host Disease?

44
Q

Symptoms of Graft vs. Host Disease?

A

Water to bloody diarrhea

45
Q

What is Sigmoid Diverticular Disease?

A

Acquired pseudodiverticular outpouchings of the colonic mucosa and submucosa

46
Q

Acquired pseudodiverticular outpouchings of the colonic mucosa and submucosa

A

Sigmoid Diverticular Disease

47
Q

US common site of Diverticular Disease?

A

Left colon

48
Q

Africa/Asia common site of Diverticular Disease?

A

Right colon

49
Q

Pathogenesis of Sigmoid Diverticular Disease?

A

Unique structure of mucularis propria + increased intraluminal pressure

50
Q

Increased intraluminal pressure can lead to?

A

Sigmoid Diverticular Disease

51
Q

Symptoms of Sigmoid Diverticular Disease?

A

Asymptomatic
Cramping and abdominal discomfort with intermittent constipation/diarrhea
- Sensation of never fully emptying the rectum

52
Q

Symptoms of Sigmoid Diverticular Disease

A

Asymptomatic
Cramping and abdominal discomfort with intermittent constipation/diarrhea
- Sensation of never fully emptying the rectum

53
Q

Sensation of never fully emptying the rectum can be seen with?

A

Sigmoid Diverticular Disease

GI - 2 (61 decks)

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