199 - Enterovirus, Parechovirus, and Reovirus Infections Flashcards
Enterovirus __ in the GI system but do not normally cause __.
multiply
gastroenteritis
Enterovirus are sensitive to __ disinfection but not __ or __.
chlorine
soap
alcohol
Common enteroviruses relevant to human are: 3
coxsackievirus
poliovirus
echovirus
Poliovirus transmission is by __
ingestion
After infection, poliovirus reaches the GI __- mostly the __ patches. From there it moves to regional __, and then to the __- first viremia.
mucosa
Peyer’s
LN
blood
Eventually it reaches the posterior __ cells.
horn
Incubation period of poliovirus is __.
2-14 days
Young children __ develop significant disease when exposed to poliovirus, unlike older children/adults which may develop __.
do not
paralysis
What are the 5 possible presentations of poliovirus?
abortive poliomyelitis non paralytic poliomyelitis paralytic poliomyelitis vaccine associated poliomyelitis post polio syndrome
Abortive poliomyelitis characteristics include: 5. The symptoms usually pass after 3 days
fever
lethargy+ myalgia
sore throat
headache
Non paralytic poliomyelitis- aseptic __. CSF will show __, normal __, and normal/slightly elevated __.
meningitis
lymphocytic pleocytosis
glucose
protein
Paralytic poliomyelitis is more common in: 3
adults
pregnancy
physical exertion
Paralytic poliomyelitis starts with __ meningitis-> strong __/__ pain->__.
aseptic
back/neck
weakness
Children may experience - paralytic poliomyelitis.
bi-phasic
Paralytic poliomyelitis weakness tens to involve mostly the __ and is usually __. The paralysis usually does not continue after the __ is relieved.
legs
asymmetric
fever
Which patients are in increased risk for vaccine associated poliomyelitis?
hypo/agammaglobulinemia
In children, enterovirus are the most common cause for __ __ and unspecific __.
aseptic meningitis
fever
Generalized disease of the new born are the most severe enterovirus infections, happen at the 1st week of life. lab results may show: 4
leukocytosis
thrombocytopenia
increased liver functions
pleocytosis in CSF
Generalized disease of the new born symptoms may include: 5
myocarditis hypotension fulminant hepatitis DIC meningitis / meningoencephalitis
Pleurodynia= __
Bornholm disease
Pleurodynia is characterized by: 2
fever
stinging pleuritic spasm/stinging abdominal pain
What is the common pathogen causing pleurodynia?
coxsackievirus
coxsackievirus is one of the most common pathogen causing __ and __ in children/newborn.
myocarditis
pericarditis
