161 - Shigellosis

Question 1

Shigella is a G(_) bacteria know to cause __

Answer 1

-

dysenteriae

Question 2

Shigella transmission is -, but also via __, __, __.

Answer 2

fecal oral
food
sex
flies

Question 3

Name the 4 serotypes of shigella:
A-
B-
C-
D-

Answer 3

A- dysenteriae
B- flexneri
C- boydii
D- sonnei

Question 4

Shigella present first with __. This ___ originates from the __

Answer 4

watery diarrhea
secretory diarrhea
jejunum

Question 5

Shiga toxin is produced by shigella __ type _

Answer 5

dysenteriae

1

Question 6

If Shiga toxin reaches the kidneys __ will occur

Answer 6

HUS

Question 7

What are the 4 classical phases of shigella?

Answer 7

incubation
watery diarrhea
dysenteriae (non compulsory)
post infection

Question 8

How long does shigella incubation lasts?

Answer 8

1-4 days (8 at most)

Question 9

What are shigella’s first symptoms? 4

Beside those, remember that abdominal discomfort/cramping/vomiting/tenesmus can also occur

Answer 9

fever
watery diarrhea
lethargy
anorexia

Question 10

Dysenteriae characteristics are: __-__ lasting diarrhea in __ quantities. ___ is common.

Answer 10

watery
bloody
small
dehydration

Question 11

During dysenteriae acute __ can occur. It involves the distal __ and __.

Answer 11

colitis
colon
rectum

Question 12

The post infectious phase is know to involve __ complications.

Answer 12

immunological

Question 13

S. flexneri is the only strain that can cause __. It appears - after the infection and is more common in people with __.

Answer 13

reactive arthritis
weeks-months
HLA-B27

Question 14

What life threatning complication are possible in shigella infections? 5

Answer 14

toxic megacolon
perforation
rectal prolapse
metabolic (hypoglycemia/hyponatremia/dehydration)
bacteremia

Question 15

What is the first line of treatment for shigella?

Answer 15

ciprofloxacin

Question 16

What is the second line of treatment for shigella?

Answer 16

pivmecillinam
ceftriaxone
azithromycin