163 - Cholera and Other Vibrioses

Question 1

Cholera is a __ disease which can cause __ and __ within hours.

Answer 1

diarrhea
dehydration
death

Question 2

Which serotypes of V. cholera cause the disease?

Answer 2

O1

O139

Question 3

Cholera transmission is via contaminated __/__.

Answer 3

water

food

Question 4

The following people will be more susceptible to cholera infections: 3

Answer 4

hypochlorhydria
using gastric anti acid
O blood type (AB are the most protected)

Question 5

Symptoms __ or __ appear.

Answer 5

may

may not

Question 6

Symptomatic patients will start showing symptoms after - h post inoculation.

Answer 6

24-48

Question 7

Diarrhea will be __, un-__, and can progress to __.

Answer 7

watery
painful
vomiting

Question 8

Water loss can get up to __ ml/kg in the first 24 hours

Answer 8

250

Question 9

Death can occur if __ and __ are not provided.

Answer 9

water

electrolytes

Question 10

__ is not usually present, but __ is more likely.

Answer 10

fever

muscle cramping

Question 11

What are the ‘rice water like’ cholera typical diarrhea characteristics? 4

Answer 11

nonbilious
grey
cloudy with mucus
fish like smell

Question 12

Dehydration symptoms are present, can can lead to __

Answer 12

kidney parenchyma necrosis

Question 13

What are the typical lab results of symptomatic people suffering from cholera? 5

Answer 13

elevated hematocrit (but not anemic)
neutropenia
elevated urea and Cr
reduced HCO3 and high anion gap
normal Na/K/Cl

Question 14

Treatment will be based on rehydration (use __), eating __. If medium-severe add Abx (__).

Answer 14

ORS
rice
macrolides

Question 15

V. vulnificus is another vibrio pathologic strain. Transmission is through __/__. The disease involves the __/__ .

Answer 15

sea water
clams
GI
soft tissue

Question 16

V. parahaemolyticus is the leading strain causing sea food __.

Answer 16

enteritis

Question 17

V. parahaemolyticus symptoms include: __, __, __, and __

Answer 17

watery diarrhea
nausea
abdominal pain 
vomiting 
fever

Question 18

V. parahaemolyticus incubation lasts between -, and symptoms last for __ days

Answer 18

4 hours- 4 days

3

Question 19

Non O1/0139 V. cholerae strains will not cause cholera. Symptoms are not __ restricted and may require Abx treatment- __/ __/ __

Answer 19

GI
tetracyclines
ciprofloxacin
3rd gen cephalosporins

Question 20

V. vulnificus is rare, seen mostly in __ > __ from __ areas. It can cause __,and __ in patients without comorbidity.

Answer 20

men
40
beachy
sepsis
wounds infections

Question 21

Other V. vulnificus in risk patients for V. vulnificus are: 4

Answer 21

hemochromatosis
hematopoietic
CKD
liver cirrhosis

Question 22

V. vulnificus incubation is _ hours, and symptoms include:

Answer 22

16
fever+ chills
fatigue 
hypotension
limb cutaneous signs

Question 23

What is the treatment for V. vulnificus?

Answer 23

empiric Abx- tetracyclines/fluoroquinolones/ cephalosporines