139 - Treatment and Prophylaxis of Bacterial infections

Question 1

Which Abx belong to the B-lactams?

Answer 1

penicillin
cephalosporines
monobactam
carbapenem

Question 2

Which Abx belong to the glycopeptide and lipoglycopeptides?

Answer 2

vancomycin

teicoplanin

Question 3

Both __ and __ Abx are cell wall inhibitors

Answer 3

B-lactams

glycopeptide

Question 4

Protein synthesis inhibitor Abx inhibit bacterial ribosomes (__/__). Most of them are __ beside __ which are bacteriocidic

Answer 4

30s
50s
bacteriostatic
aminoglycosides

Question 5

Mention 3 aminoglycosides:

Answer 5

streptomycin
amikacin
gentamicin

Question 6

Aminoglycosides attach to the sub unit of __s ribosome

Answer 6

30

Question 7

Which Abx are protein synthesis inhibitors?

Answer 7

aminoglycoside
tetracycline
macrolides
lincosamides

Question 8

Tetracycline attach to the sub unit of __s ribosome

Answer 8

30

Question 9

Macrolides attach to the sub unit of __s ribosome

Answer 9

50

Question 10

Mention 3 macrolides:

Answer 10

azithromycin
clarithromycin
erythromycin

Question 11

Mention 2 folate synthesis Abx groups:

Answer 11

sulfonamides

trimethoprim

Question 12

Name 3 sulfonamides:

Answer 12

sulfisoxazole
sulfadiazine
sulfamethoxazole

Question 13

Name the 4 DNA/RNA synthesis inhibitors Abx groups:

Answer 13

quinolones
rifamycin
nitrofurantoin
metronidazole

Question 14

List 3 quinolones:

remember they inhibit DNA synthesis

Answer 14

levofloxacin
ciprofloxacin
moxifloxacin

Question 15

___ is a well membrane Abx

Answer 15

daptomycinq

Question 16

__ is a nephrotoxic Abx which when given at a __rate may cause red man syndrome

Answer 16

vancomycin

high

Question 17

__ is a nephrotoxic and __ Abx which may cause both vestibular and cochlear damage

Answer 17

aminoglycosides

Question 18

__ is an hepatoxic Abx. The risk increase when it is given with other anti TB drugs

Answer 18

rifampin

Question 19

Linezolid can cause __, __ and __ __ and __. most of those symptoms are linked with prolonged use

Answer 19

myelosuppression
optic
peripheral
neuropathy
lactic acidosis

Question 20

Macrolides can cause __ distress and __ prolongation

Answer 20

GI

QT

Question 21

Linezolid increase the liver metabolism of __ making it less effective, which leads to lower __

Answer 21

coumadin

INR

Question 22

Beside being __, TMP-SMX can also lead to hypersensitivity reactions:3

Answer 22

nephrotoxic
nausea/vomiting
diarrhea
rash

Question 23

The following Abx require level adjustment to renal function: 4

Answer 23

penicillin, cephalosporins (B-lactam)
gentamycin and other aminoglycosides
vancomycin and other glycopeptide

Question 24

What is the most common mechanism of resistance against beta lactam? which bacteria is it especially true for?

Answer 24

b-lactamase

G (-)