167 - Bartonella Infections, Including Cat-Scratch Disease Flashcards

1
Q

Bartonella infection causes ___

A

CSD (cat scratch disease)

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2
Q

Typical CSD causes local __, while the atypical will lead to ___ manifestations.

A

subacute lymphadenopathy

extranodular

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3
Q

CSD primary lesion will be a small __ within days-weeks. - weeks after

A

pustule

1-3

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4
Q

The most common LN in CSD are: __->__->__->__

A

axillary
epitrochlear
head/neck
inguinal/femoral

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5
Q

50% of CSD will suffer from __, __, and __

A

fever
malaise
anorexia

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6
Q

CSD may imitate __ with __ loss, night __

A

lymphoma
weight
sweats

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7
Q

Recovering from CSD may last - until all symptoms disappear

A

weeks-months

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8
Q

Atypical CSD may or may not involve __. It will most likely include __ syndrome.

A

lymphadenopathy

Parinaud’s oculoglandular

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9
Q

What does Parinaud’s oculoglandular consists of? 4

A

granulomatous conjunctivitis
ipsilateral preauricular lymphadenitis
granular hepatitis/ splenitis
neuroretinitis

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10
Q

Patients >60 with CSD will not have __ but are more likely to suffer from __ and __.

A

lymphadenopathy
FUO
encephalopathy

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11
Q

The most used diagnostic tests for CSD is __ test

A

serological

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12
Q

__ tests are also useful for CSD diagnosis. The sample is taken from __

A

PCR

LN puss

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13
Q

CSD LN should be __. Immunocompromised should receive __ treatment.

A

aspired

ABx

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14
Q

Typical CSD is not routinely treated with ABx, beside if extensive ___ is present. In that case treat with __

A

azithromycin (macrolide)

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15
Q

Coxiella burnetii and bartonella are the most common pathogens in negative cultures ___

A

endocarditis

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16
Q

What is the best way to diagnose bartonella endocarditis?

A

serological tests with high titer IgG

17
Q

What is the empiric treatment for bartonella endocarditis?

A

gentamicin (aminoglycoside) + doxycycline (macrolide) + ceftriaxone (3rd gen cephalosporine)

18
Q

What is the reason we use ceftriaxone for bartonella endocarditis? when should we stop it?

A

to cover other HACEK

stop as soon as diagnosis is based