187 - Herpes Simplex Virus Infections (HSV) Flashcards
The most common HSV1 infection is through the __ ganglion.
trigeminal
Trigeminal nerve- __
5th cranial nerve
The most common HSV 1 genital infection is through the ___ (S2-S5)
sacral nerve root
Immunocompromised patients with ___ deficiency are more prone to severe infections, than patients with humoral deficiency (such as- __),
cellular
agammaglobulinemia
CD_ are instrumental in determining the HSV1 infection becoming __ or __.
8
clinical
subclinical
HSV2 infection increases the risk for __ during sexual intercourse with an infected individual.
HIV-1
HSV2 is more common in the __ area
genitalium
HSV1 is more common in the __ area
facial
What are the common symptoms of HSV1?
fever weakness myalgia anorexia cervical lymphadenopathy
Up to 15% of people with latent HSV will experience __ 3 days after ___.
relapse
dental extraction
HSV reactivation is common in __ and post __. It is recommended to give prophylaxis of __/__
immunocompromised
transplant
acyclovir
penciclovir
HSV 1 and __ are considered to be possible etiology for __.
VZV
Bell’s palsy
Genital HSV infection tends to be __ and __.
bilateral
painful
Herpetic Whitlow is an infection of the ___.
finger
Herpes gladiatorum is common among __, and may affect different areas of the body (__, __, __).
wrestlers
chest
ears
face
HSV eye infection is the most common cause for __.
corneal blindness
HSV eye infection = ___.
HSV keratitis
HSV keratitis should not be treated with ___
steroids
HSV keratitis should be treated with __, __, and __.
debridement
local antiviral
interferon
HSV can cause viral ___. The best diagnostic tool is CSF __.
encephalitis
PCR
HSV encephalitis should be treated with ___ before diagnosis is made.
acyclovir
HSV meningitis is usually due to primary __. Symptoms include 3 and lasts - days. CSF lymphocytic pleocytosis is a characteristics of the disease.
HSV2 headache fever photophobia 2-7
HSV is the most common cause of ___ meningitis.
Mollaret’s
The biggest risk for vertical transmission during pregnancy is the __ of infection to the time of partum.
proximity
The best diagnostic tool is __ or __-__ culture.
PCR
spin amplified
Cutaneous/mucosae HSV infections should be treated with: __/__/__.
acyclovir
famciclovir
valacyclovir
Ocular HSV infections should be treated with __/__/__.
trifluorothymidine
idoxuridine
cidofovir
Encephalitis/neonatal HSV should be treated with
IV acyclovir
What is the most common S/E for IV acyclovir? how can it be prevented?
AKI slow drip (1 hour) + hydration
