187 - Herpes Simplex Virus Infections (HSV)

Question 1

The most common HSV1 infection is through the __ ganglion.

Answer 1

trigeminal

Question 2

Trigeminal nerve- __

Answer 2

5th cranial nerve

Question 3

The most common HSV 1 genital infection is through the ___ (S2-S5)

Answer 3

sacral nerve root

Question 4

Immunocompromised patients with ___ deficiency are more prone to severe infections, than patients with humoral deficiency (such as- __),

Answer 4

cellular

agammaglobulinemia

Question 5

CD_ are instrumental in determining the HSV1 infection becoming __ or __.

Answer 5

8
clinical
subclinical

Question 6

HSV2 infection increases the risk for __ during sexual intercourse with an infected individual.

Answer 6

HIV-1

Question 7

HSV2 is more common in the __ area

Answer 7

genitalium

Question 8

HSV1 is more common in the __ area

Answer 8

facial

Question 9

What are the common symptoms of HSV1?

Answer 9

fever
weakness
myalgia
anorexia
cervical lymphadenopathy

Question 10

Up to 15% of people with latent HSV will experience __ 3 days after ___.

Answer 10

relapse

dental extraction

Question 11

HSV reactivation is common in __ and post __. It is recommended to give prophylaxis of __/__

Answer 11

immunocompromised
transplant
acyclovir
penciclovir

Question 12

HSV 1 and __ are considered to be possible etiology for __.

Answer 12

VZV

Bell’s palsy

Question 13

Genital HSV infection tends to be __ and __.

Answer 13

bilateral

painful

Question 14

Herpetic Whitlow is an infection of the ___.

Answer 14

finger

Question 15

Herpes gladiatorum is common among __, and may affect different areas of the body (__, __, __).

Answer 15

wrestlers
chest
ears
face

Question 16

HSV eye infection is the most common cause for __.

Answer 16

corneal blindness

Question 17

HSV eye infection = ___.

Answer 17

HSV keratitis

Question 18

HSV keratitis should not be treated with ___

Answer 18

steroids

Question 19

HSV keratitis should be treated with __, __, and __.

Answer 19

debridement
local antiviral
interferon

Question 20

HSV can cause viral ___. The best diagnostic tool is CSF __.

Answer 20

encephalitis

PCR

Question 21

HSV encephalitis should be treated with ___ before diagnosis is made.

Answer 21

acyclovir

Question 22

HSV meningitis is usually due to primary __. Symptoms include 3 and lasts - days. CSF lymphocytic pleocytosis is a characteristics of the disease.

Answer 22

HSV2
headache
fever
photophobia 
2-7

Question 23

HSV is the most common cause of ___ meningitis.

Answer 23

Mollaret’s

Question 24

The biggest risk for vertical transmission during pregnancy is the __ of infection to the time of partum.

Answer 24

proximity

Question 25

The best diagnostic tool is __ or __-__ culture.

Answer 25

PCR

spin amplified

Question 26

Cutaneous/mucosae HSV infections should be treated with: __/__/__.

Answer 26

acyclovir
famciclovir
valacyclovir

Question 27

Ocular HSV infections should be treated with __/__/__.

Answer 27

trifluorothymidine
idoxuridine
cidofovir

Question 28

Encephalitis/neonatal HSV should be treated with

Answer 28

IV acyclovir

Question 29

What is the most common S/E for IV acyclovir? how can it be prevented?

Answer 29

AKI
slow drip (1 hour) + hydration