146 - Listeria Monocytogenes infections Flashcards
Listeria is G(_), can grow even in __ and comes from __. It is dangerous mostly for __ and __
\+ frost rotten food pregnant women immunocompromised
Listeria is found mostly in soft__, deli __/__,__, cold __
cheese
meat/cold-cut
milk
salads
Diagnosis of listeria is made with __/__/__ cultures
blood
CSF
amniotic fluid
What are the main groups of clinical sings of listeria:
GE (gastroenteritis)
bacteremia
meningitis
meningoencephalitis/focal CNS infections
Listeria causes GE after __ h. symptoms include: 3. If the GE is isolated __ is not needed.
48 diarrhea fever headache Abx
Listeria bacteremia causes: 3. We should suspect bacteremia when neurological symptoms are present.
Consider __ in pregnant women even w/o CNS symptoms
fever
chills
myalgia/arthralgia
LP
Listeria meningitis should be suspected in elders/chronic patients with ____. We will see less__ signs and __ and more __ and __.
aseptic meningitis meningeal photophobia focal seizures
The CSF of patients with listeria meningitis will show - WBC with __ dominance, low __ and positive __. in 30-40% __ is possible
100-1000 neutrophils glucose gram stain hydrocephalus
Meningoencephalitis/focal CNS infection due to listeria has a __ prodrome with __ and __ followed by __ and focal signs. MRI + gadolinium is the test of choice- looking for ___ lesions
biphasic fever headache decent ring enhancing
Meningoencephalitis/focal CNS infection due to listeria has a __ prodrome with __ and __ followed by __ and focal signs. MRI + gadolinium is the test of choice- looking for ___ lesions
biphasic fever headache decent ring enhancing
Pregnant women with __, __/__/__/__ pain should be tested for listeria. __ is usually present.
fever
muscle/joint/back/head
bacteremia
Listeria may cause complications during pregnancy such as __ and __ are possible. _% of fetus get infected and of them __ die. From the ones that are born _% die.
preterm birth miscarriage 80 50 20
Treatment for listeria is with high dose IV __ with or without __. If allergic __.
ampicillin
gentamicin
TMP-SMX
Listeria + bacteremia should be treated for _ weeks, newborn for _ weeks, meningitis for -, brain abscess/encephalitis for -
2
3
4-6
6-8