Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Wrongs > uworld exam 2 :( > Flashcards

uworld exam 2 :( Flashcards

1
Q

can hemoptysis happen with rheumatic fever

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Peutz-Jeghers

A

aut dom- STK11- chrom 19

pigmented mucocutaneous macules, hamartomatous polyps in GI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

pancoast tumor produces horner’s through compressing what

A

superior cervical ganglion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

are coronary arteries normal in HOCM

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

which DNA pol removes RNA primer and replaces it with DNA

A

DNA pol I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

lynch syndrome is a defect in what?

A

mismatch repair

–> colorectal, ovarian, endometrial cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

abdominal pain, free under air diaphragm, guarding

A

bowel perforation, periotinitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

metaclopramide contra

A

parkisonian features- trigger EPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

alkaptonuria enzyme defect

A

homogentistic acid deioxygenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

alkpotunuria symptoms

A

black urine
black skin pigments on ear, sclera
deposit in joint cartilage–> osteoarthropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how do you differentiate between marfan and homocystinuria

A

disolocation of lens upward- marfan

downard- homocystinuria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

why is heparin better in pregnancy

A

water soluble- cant cross placenta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

cystic hygroma

A

soft compressible masses that transilluminate (head and neck area)

due to lymphatics not connect to veins

associated with karyotype abnlormaties

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what ion flow contributes to lesser amplitude in cell deporalization

A

less extracellular Na –> less gradient of it wanting to come in –> less amplitude

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

cyclosporine MOA

A

calcineurin inhibitor- inhibit IL-2 txn

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

dopamine beta hydroxylase

A

converts dopamine –> NE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

negri bodies

A

esoinophilic inclusions in hippocampus (rabies)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what happens with a renal artery clip?

A

Renal plasma flow drops

GFR stays the same due to autoregulation

So filtration fraction increases!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

treatment for psoriasis

A

retinoids (acitretin)

20
Q

orlistat MOA

A

inhibits intestinal lipase- decreased intestinal fat absorption

–> weight loss

but GI side effects

21
Q

venous drainage above dentate line

A

superior rectal vein–> inferior mesenteric vein –> portal system

22
Q

venous drainage below dentate line

A

middle and inferior rectal veins –> internal iliac vein–> systemic circulation

23
Q

17 alpha hydroxylase deficiency

A

no cortisol or androgens
hypertension (high MR)

cant convert progesterone to 17 hydroxyprogesterone

24
Q

spider angiomatas in cirrhosis caused by

A

hyperestrogenism

25
Q

In agglutination inhibition test, the presence of agglutination is positive or negative

A

negative pregnancy test

26
Q

paclitaxel MOA and Rx

A

prevents microtubule breakdown –> cell cycle arrest

during stent: prevents restenosis by preventing intimal hyperplasia

27
Q

what originates on the distal clavicle

A

deltoid and SCM

28
Q

kayser-flesicher rings deposits copper where

A

cornea

29
Q

melanoma mutation

A

CDKN2A on chrom 9

30
Q

does flumazenil affect barbituates

A

no

31
Q

leucine zippers are what

A

txn factors

32
Q

where in the cell is purine and pyrimidine synthesis

A

starts in cytosol

then nucleus

33
Q

psoas test is a sign of …

A

appendicitis

psoas abscesses

34
Q

alcoholism causes what kind of cardiomyopathy

A

dilated

35
Q

how do retinoids help treat acne

A

decreased sebum

normalize epidermal differentiation-

increases cell turnover- open blocked pores and reduce hyperkeratinization

36
Q

what does the esophagus hiatus in the diaphragm contain

A

esophagus

trunks of vagus

37
Q

what does the aorta hiatus contain in the diaphragm

A

aorta
thoracic duct
azygos vein

38
Q

dihydropyridine CCB list and action

A

amlodipine
nefidipine
felodipine

selective for vascular smooth muscle –> vasodilate to reduce afterload

39
Q

glucokinase (versus hexokinase)

A

in pancreatic beta cells (insulin secretion)

in liver (glycogen synthesis)

lower affinity for glucose (so needs high glucose to be activated)

40
Q

maturity onset diabetes of the young is a defect in…

A

glucokinase or associated txn factors

41
Q

findings of DIC

A

high PT and PTT
thrombocytopena
decreased fibrinogen

complication of sepsis

42
Q

vertebral disc herniation

A

disrupt annulus fibrosus and prolapse of nucleus pulposus

43
Q

which bacteria produce H2S

A

salmonella, proteus

44
Q

pontine hemorrhages cause…

A 
pinpoint pupils
loss of horizontal gaze
quadriparesis
decerebrate posturing
coma
45
Q

how do intracerebral neoplasms cause increased ICP

A

disrupt BBB–> leak vasogenic edema–> midline shift

CSF obstruction

Wrongs (36 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions