6/2 Flashcards
which anemia is a splenectomy indicated
hereditary spherocytosis
drug to treat ulcerative colitis
sulfasalazine
does uric acid precipitate at high or low pH?
low pH
areas of nephron with lowest pH
collecting duct, distal tubule
if someone with leukemia develops multiple uric acid crystals. think…
tumor lysis syndrome- emergency!
where is PAH secreted into
proximal tubule
pathogenesis of paraneoplastic cerebellar degeneration (from small cell lung carc, breast, ovarian, uterine cancer)
autoimmune- cross react with purkinje neuron antigens
anti yo, p/q, hu
order of arteries involved in atherosclerosis
abdominal aorta > coronary > popliteal > interanl carotid > circle of Willis
lymph flow in lower extremeties
medial tracts–> inguinal LAD
lateral tracts –> popliteal and inguinal LAD
if someone with RA develops sensory loss and weakness, think…
vertebral subluxation –> spinal cord injury
neuroblastoma
develops from adrenal medulla
high n-myc
opsoclonus-myoclonus paraneoplastic
spinal stenosis
lumbar region
weakness, pain, paresthesia
better with certain postures- leaning over, walking uphill
degernative arthritis –> IV disc herniation, ligamentum flavum hypertrophy, osteophyte
tryptase
enzyme specifically related to mast cells
increased in anaphalyxis
mechanism to induce insulin resistance
activate serine or threonine kinases to phosphorylate beta subunits on insulin receptor
dont by TNF alpha, catecholamines, glucagon, glucocorticoids
where does parvovirus b19 replicate?
erythrocyte precursors in bm
which ulcers are not associated with increased risk of cancer?
duodenal
what is normal in ARDS
pulmonary capillary wedge pressure
leflunomide MOA and RX and TX
MOA: reversibly inhibits dihydroorate dehdrogenase - prevents pyrmidine synthesis and suppress T cell proliferatio
Rx: RA, psoriasis
Tx: diarrhea, hepatox, HTN, teratogen
TNF inhibitors
Etanercept- TNF decoy fusion protein
Infliximab, adalimumab- mabs
glucagonoma presentaiton
hyperglycemia (newly presented diabetes)
necrolytic migratory erythema (blistering erythematous plaque with central clearing)- groin, face, extremities
what kind of cancer can Rb give later in life
osteosarcomas
congenital torticollis
2-4 weeks
cause: malposition of head during utero or birth trauma
head tilted to one side, soft tissue mass, SCM fibrosis
DOC for delirium
haloperidol
musculoskeletal provides sensory innervation to what part
lateral forearm
murmur associated with head bobbing
aortic regurgitation
