5/25 Flashcards
RPF equation
RPF= RBF (1-Hct)
arginase deficiency
elevated arginine in urea cycle, but cant convert to urea
spastic diplegia, abnormal movements
treat- low protein diet (low arg)
normal A-a gradient
5-15 mm Hg
examples of increased A-a gradient
V/Q mismatch (eg. COPD, pneumonia)
R–>L shunt (congenital heart shunts)
diffusion impairment (eg. ARDS)
L–type Ca channels in skeletal muscle vs smooth muscle and cardiac cells
skeletal: L-type channels directly stimulate Ryr channels to release Ca from SR
smooth/cardiac: L type channels –> Ca influx –> Ca opens Ryr channels to release Ca from SR
(target of CCBs)
mid-systolic clic plus mid-late systolic murmur
mitral valve prolapse
which HIV protein is glycosylated
env- to make GP160–> GP120, GP41
which rib is left kidney at
12th
which ribs are spleen at
9-11th
best indicator of mitral stenosis prognosis
A2 to opening snap time (shorter–> more severe)
bioavailability equation
F= (AUC oral x dose IV) / (AUC IV x dose oral)
highly vascularized compartments (will get lipophilic drug flow first)
brain, kidney, liver, lungs, heart
not well vascularized compartments (delayed distribution of drug)
skeletal muscle, bone, fat
intestinal malrotation of midgut
intestinal obstruction (compression by adhesive bands- Ladd’s bands) –> billous emesis
midgut volvolus (twist around SMA –> ischemia)
CD21
present on B cells - cell receptor for C3d complement
EBV binds this via gp350
what’s prone to injury in pelvic surgery
ureters! –> hydronephrosis
fenofibrate MOA
activate PPARalpha –> decreased hepatic VLDL, increased LPL, decrease TG’s, mildly elevate HDL
which cholesterol lowering drug is best at reducing CV events
statins
treatment for narcolepsy
psychostimulants- modafinil
2nd line- amphetamines
PrP
prion
where is resistance the highest in pulm tree
mid-sized bronchioles - high turbulent
trachea is wide, and smaller has large cross-sectional area
pseudotumor cerebri
idiopathic intracranial hypertension
young obese women
daily HA, bilateral papilledema, transient visual dist.
increased ICP –> impaired axoplasmic flow and optic disc edema
hepatocyte histo specific for hep B
ground glass hepatocytes- finely granular, diffusely homogenous, pale eosinophilic
contact precautions for c dfi
nonsterile gloves and gown
wash hand with soap
lab finding for acute bacterial parotitis
elevated serum amylase
where is SA node
RA near SVC opening
if DVT turns into artery embolism, what is going on?
ASD or patent foramen ovale
most common trigger of DIC in pregnant woman
release of tissue factor (thromboplastin) from injured placenta into maternal circulation
paraneoplastic syndromes with small cell lung carc
SIADH
Cushings- ACTH
Lambert-Eaton
Cerebellar ataxia
paraneoplastic syndromes with lung SCC
PTHrp- hypercalcemia
paraneoplsatic syndromes with lung adenocarcinoma
hypertrophic osteoarthropathy
dermatomyositis, polymyositis
migratory thrombophlebitis
