Rx Wrongs Flashcards
Order of conduction velocity from fastest to slowest
Purkinje–>His–>AV
Dialtizem MOA
CCB- nondihydropyridines- prolong PR interval-inhibit voltage gated Ca channels
SCID enzyme defect
adenosine deaminase- purine salvage pathway- DNA synthesis for T and B cells
Amiodarone MOA and Tx
MOA: Class III- block K+ channels to prolong repolarization
Tx: Pulmonary fibrosis, hepatotoxicity, hypo/hyperthryoidism
Skin condition in Rheumatic Fever
erythema marginatum
Wilms Tumor Chromosome number
Chromosome 11
Meckel’s diverticulum epidemiology
2 rule: 2% population, 2x more in boys, <2 yo, 2 feet from ileocecal valve, 2 inches long, 2 types of heterotopic mucosa
Meckel’s diverticulum cause
failure of involution of vitelline duct–> intestinal obstruction
ketoconzacole adverse reaction
liver dysfunction
Rifampin
orange tint to secretions!
MOA: inhibit DNA-dep RNA pol –> RNA synthesis
ethosuximide MOA
block T type calcium channels
dermatome level of inguinal ligament
L1
Marfan syndrome genetic defect
aut dom fibrillin 1
which nerve innervates medial thigh (adductor muscles)?
obturator nerve
metochlopramide
for gastroparesis in DM2. DA antagonist and increases LES tone
wet, wacky, wobbly
normal pressure hydrocephalus- from increased CSF (enlarged ventricles) by tumors or from impaired reabsorption (super sagittal vein) from tumors or meningitis.
1st branchial arch
M- mandible, malleus, sphenoMandibular ligament, musclles of mastication (temporalis, masseter, medial and lateral pterogoids)
DiGeorge syndrome
defect of 3rd and 4th branchial pouches- no thymus
CATCH 22- cardiac defects, abnl facies, thymic hypoplasia, cleft palate, hypocalcemia due to microdeletion on chrom 22
what drug will reverse the myelosuppression from methotrexate?
leucovorin
Turners is associated with what heart defect
juxtaductal coarctation of aorta
postductal coarctation of aorta
BP in upper extremities significantly higher than lower.
rib notching
high risk of bacterial endocarditis and cerebral hemorrhage
cystic fibrosis main symptom buzzwords
steatorrhea, infertility, chronic persistent cough
pseudomonas infections
Goodpasture associated with exposure to what?
hydrocarbon solvents
lactobacillus is what type of bacteria
gram positive facultative anaerobes
SSPE symtoms
- demyelinate CNS–> personality changes, dementia (1 year)
- myoclonus (3-12 months)
- worsening dementia and ANS, and rigidity and flaccidity
IL-2 helps treat
metastatic renal cell carcinoma
autoimmune hemolytic anemia lab findings
positive Coombs test; high LDH, high indirect bilirubin, low haptoglobin
which artery gets tangled in a fused horseshoe kidney?
inferior mesenteric artery
which heart defect do patients with lyme disease have?
AV node block
spermatids (N) and spermatogonium (2N) are located where in the seminiferous tubule? apical or basal?
Spermatogonia- begin meiosis at basal layer
Spermatids- apical layer
indirect versus direct hernia
indirect: congenital- processus vaginalis remains open
direct: older men- weakness in abdominal wall
alpha 1-antitrypsin deficiency leads to what two conditions?
panacinar emphysema and liver cirrhosis
antibody associated with dermatomyoitis
anti-jo-1
what can treat IBS
loperamide
what two types of ectopic tissue is in meckel’s diverticulum?
pancreatic and gastric
what is the treatment regimen for Hodkin lymphoma?
Doxorubicin, Vinblastine, bleomycin, dacarbazine
which organ is the last to begin hematopoiesis
bone marrow
cremaster muscle is extension of what muscle?
internal oblique
dressler syndrome
autoimmune fibrinous pericarditis–> pericardial frictional rub
which CN controls jaw muscles?
5- V3
down syndrome is a defect in which stage of cell division
Meiosis I- anaphase
what is associated with a tracheoesophageal fistula?
polyhydromnios- cant swallow amniotic fluid
