Rx Wrongs Flashcards

1
Q

Order of conduction velocity from fastest to slowest

A

Purkinje–>His–>AV

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2
Q

Dialtizem MOA

A

CCB- nondihydropyridines- prolong PR interval-inhibit voltage gated Ca channels

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3
Q

SCID enzyme defect

A

adenosine deaminase- purine salvage pathway- DNA synthesis for T and B cells

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4
Q

Amiodarone MOA and Tx

A

MOA: Class III- block K+ channels to prolong repolarization

Tx: Pulmonary fibrosis, hepatotoxicity, hypo/hyperthryoidism

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5
Q

Skin condition in Rheumatic Fever

A

erythema marginatum

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6
Q

Wilms Tumor Chromosome number

A

Chromosome 11

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7
Q

Meckel’s diverticulum epidemiology

A

2 rule: 2% population, 2x more in boys, <2 yo, 2 feet from ileocecal valve, 2 inches long, 2 types of heterotopic mucosa

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8
Q

Meckel’s diverticulum cause

A

failure of involution of vitelline duct–> intestinal obstruction

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9
Q

ketoconzacole adverse reaction

A

liver dysfunction

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10
Q

Rifampin

A

orange tint to secretions!

MOA: inhibit DNA-dep RNA pol –> RNA synthesis

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11
Q

ethosuximide MOA

A

block T type calcium channels

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12
Q

dermatome level of inguinal ligament

A

L1

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13
Q

Marfan syndrome genetic defect

A

aut dom fibrillin 1

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14
Q

which nerve innervates medial thigh (adductor muscles)?

A

obturator nerve

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15
Q

metochlopramide

A

for gastroparesis in DM2. DA antagonist and increases LES tone

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16
Q

wet, wacky, wobbly

A

normal pressure hydrocephalus- from increased CSF (enlarged ventricles) by tumors or from impaired reabsorption (super sagittal vein) from tumors or meningitis.

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17
Q

1st branchial arch

A

M- mandible, malleus, sphenoMandibular ligament, musclles of mastication (temporalis, masseter, medial and lateral pterogoids)

18
Q

DiGeorge syndrome

A

defect of 3rd and 4th branchial pouches- no thymus

CATCH 22- cardiac defects, abnl facies, thymic hypoplasia, cleft palate, hypocalcemia due to microdeletion on chrom 22

19
Q

what drug will reverse the myelosuppression from methotrexate?

A

leucovorin

20
Q

Turners is associated with what heart defect

A

juxtaductal coarctation of aorta

21
Q

postductal coarctation of aorta

A

BP in upper extremities significantly higher than lower.
rib notching
high risk of bacterial endocarditis and cerebral hemorrhage

22
Q

cystic fibrosis main symptom buzzwords

A

steatorrhea, infertility, chronic persistent cough

pseudomonas infections

23
Q

Goodpasture associated with exposure to what?

A

hydrocarbon solvents

24
Q

lactobacillus is what type of bacteria

A

gram positive facultative anaerobes

25
Q

SSPE symtoms

A
  1. demyelinate CNS–> personality changes, dementia (1 year)
  2. myoclonus (3-12 months)
  3. worsening dementia and ANS, and rigidity and flaccidity
26
Q

IL-2 helps treat

A

metastatic renal cell carcinoma

27
Q

autoimmune hemolytic anemia lab findings

A

positive Coombs test; high LDH, high indirect bilirubin, low haptoglobin

28
Q

which artery gets tangled in a fused horseshoe kidney?

A

inferior mesenteric artery

29
Q

which heart defect do patients with lyme disease have?

A

AV node block

30
Q

spermatids (N) and spermatogonium (2N) are located where in the seminiferous tubule? apical or basal?

A

Spermatogonia- begin meiosis at basal layer

Spermatids- apical layer

31
Q

indirect versus direct hernia

A

indirect: congenital- processus vaginalis remains open
direct: older men- weakness in abdominal wall

32
Q

alpha 1-antitrypsin deficiency leads to what two conditions?

A

panacinar emphysema and liver cirrhosis

33
Q

antibody associated with dermatomyoitis

A

anti-jo-1

34
Q

what can treat IBS

A

loperamide

35
Q

what two types of ectopic tissue is in meckel’s diverticulum?

A

pancreatic and gastric

36
Q

what is the treatment regimen for Hodkin lymphoma?

A

Doxorubicin, Vinblastine, bleomycin, dacarbazine

37
Q

which organ is the last to begin hematopoiesis

A

bone marrow

38
Q

cremaster muscle is extension of what muscle?

A

internal oblique

39
Q

dressler syndrome

A

autoimmune fibrinous pericarditis–> pericardial frictional rub

40
Q

which CN controls jaw muscles?

A

5- V3

41
Q

down syndrome is a defect in which stage of cell division

A

Meiosis I- anaphase

42
Q

what is associated with a tracheoesophageal fistula?

A

polyhydromnios- cant swallow amniotic fluid