5/6

Question 1

drugs of zero order kinetics

Answer 1

phenytoin
ethanol
aspirin
(pea)

Question 2

sulfa drugs

Answer 2

sulfonamide antibiotics
sulfasalazine
sulfonylureas
probenecid
furosemide
thiazides
actezolamide
celecoxib

Question 3

cyp inducers

Answer 3

chronic alcoholics
st johns wort
phenytoin
phenoarbital
nevirapine
rifampin
griseofulvin
carbamazepine

chronic alcoholics steal phen-phen and never refuse greasy carbs

Question 4

cup inhibitors

Answer 4

acute alcoholic abuse
ritonavir
amiodarone
cimetidine
ciprofloxacin
ketoconazole
sulfonamides
isoniazid
grapefruit juice
quinidine
macrolides (except azithromycin)

AAA RACKS In GQ Magazine

Question 5

Short bowel syndrome

Answer 5

occurs with small bowel resection or Crohns

loss of absorptive surface area –> watery diarrhea and loss of macro and micronutrients (think B12)

Question 6

obesity-related restrictive lung disease

Answer 6

reduction in chest wall compliance and lung compliance (microatelectasis)

decreased ERV, TLC, FEV1, FVC
normal RV

Question 7

PKU signs and pattern of inheritance

Answer 7

aut rec

intellectual disability, eczema, gait abnormality, musty body odor

Question 8

giant cell arteritis symptoms

Answer 8

systemic- fever, malaise, weight loss
HA
jaw claudication
visual disturbances
polymyalgia rheumatica

granulomatous inflammation of media

Question 9

spinal muscular atrophy mutation

Answer 9

survival motor neuron 1 gene SMN1

encodes small nuclear ribonucleoproteins

Question 10

which cells in brain would have lipid after an infarct?

Answer 10

microglia after a week of infarct

phagocytosis of myelin breakdown products

Question 11

signs of HOCM

Answer 11

family history of premature sudden death
chest discomfort
crescendo-decrescendo systolic murmur that accentuates when you go from supine to standing

Question 12

contra drugs for HOCM

Answer 12

Vasodilators (dihydropyridine CCB, nitroglycerin, ACEI)- decrease SVR

Diuretics- decrease preload

Question 13

drugs that help HOCM

Answer 13

negative inotropic agents- beta blockers, nondihydropyridine CCB, disopyramide

Question 14

what’s bigger in COPD? TLC or RV (relatively)

Answer 14

RV, but both increase

Question 15

acute compartment syndrome

Answer 15

increase in pressure within fascia compartments (from fractures, crush injuries, thermal disorders, vascular)

most often in anterior compartment- foot extensor muscles, anterior tibial artery, deep peroneal nerve

Question 16

cell deficiency in localized versus systemic candida infections

Answer 16

localized- T cells

systemic (hematogenous)- neutropenia

Question 17

what causes dimpling of the breast

Answer 17

malignant infiltration of suspensory ligament of breast

Question 18

left versus right sided frontal lobe lesions

Answer 18

left- apathy, depression

right- disinhibiton

Question 19

which race has greatest bone density

Answer 19

african americans

Question 20

CSF findings of cryptococcus meningitis

Answer 20

low glucose, moderate increase in proteins, low leukocytes (HIV), lymphocytes predominate

Question 21

is methacholine asthma test more sensitive or specific?

Answer 21

very sensitive, not specific

Question 22

celiac trunk supplies what?

Answer 22

stomach
part of duodenum
gallbladder
liver
spleen
pancreas

Question 23

most common pituitary adenoma

Answer 23

prolactinoma

Question 24

most common cause of retinitis in HIV patients?

Answer 24

CMV

Question 25

Enoxaparin MOA

Answer 25

low molecular weight heparin

binds/activates AT III and stops factor Xa from converting prothrombin to thrombin

Question 26

Ecoli’s toxins and associated diseases

Answer 26

Fimbrae- UTIs

K1 capsular polysacch- neonatal meningitis

LPS- bacteremia, septic shock

verotoxin (shiga-like)- bloody stool

heat stable/labile toxin- watery diarrhea

Question 27

which polyp is more likely to become malignant? tubular or villous?

Answer 27

villous

Question 28

psoriasis histology

Answer 28

hyperkeratosis
acanthosis
elongation of rete ridges
mitotic activity above epidermal basal layer
reduced stratum granulosum
thinned epidermis above papillae- auspitz