The Cell Cycle Flashcards
what are the main stages of the cell cycle?
interphase and mitotic phase
what are the stages within interphase?
G1 phase, S phase, and G2 phase
what are the stages within the mitotic phase?
prophase, metaphase, anaphase, telophase
interphase
- resting between cell division (which is a non-mitotic phase)
- very active
- gearing up for mitotic phase
G1 phase
- normal cellular activities
- normal cell growth
- normal duplication of organelles
- protein synthesis
S phase
- DNA replication occurs
- most vulnerable phase (which can cause DNA damage since replication of DNA occurs during this stage)
G2 phase
-synthesis of protein and microtubules (in the centriole)
mitotic phase
- nuclear division
- cytokinesis: cytoplasmic division
what are some possible fates of mitotic products (daughter cells)?
- differentiate (specialize) –> age –> die
- rest as an “uncommitted” cell
- enter a new cell cycle immediately (which has a rapid mitotic rate)
what two things vary with cell type?
- the capacity to grow and divide
- the rate at which these processes occur
what are the three main cell categories?
- cells that are extremely specialized and have lost their ability to divide
- cells that normally do not divide, but can be induced to do so by a stimulus
- cells which continuously undergo cell division
what are cells with a high mitotic rate subject to?
destruction, irritation, and friction
what are some types of cells that are extremely specialized and have lost their ability to divide? and why?
- red blood cells (matured only) (since it has no nucleus)
- neuron (nerve cell) (bc there’s no centrioles)
- muscle cell (cell may increase in size, not in number)
what are some types of cells that normally do not divide but can be induced to do so by a stimulus?
- liver cells
- lymphocytes (white blood cells)
what are some types of cells which continuously undergo cell division?
- skin (constantly replaced)
- cells of the intestinal lining
- bone marrow cells
what does it mean when cells are continuously undergoing cell division?
- it means that they’re flipping through the S phase
- more chances for error in genetic replication
- may lead to mutations
chromosome
- dark- staining, thread-like body in the nucleus
- composed of DNA and protein
- contains genetic information
chromatid
- duplicated chromosome
- hooked together through centromere
gene
unit of DNA that provides the instructions for the production of a specific protein
centriole
- composed of microtubules
- 2 cylindrical structures
- serves as ongoing center for the mitotic spindle
mitotic spindle composition
composed of microtubules
karyotype
- the number and type of chromosomes an individual has
what do the amount of autosomes you have determine?
how well controlled the body structure and metabolism is
how many chromosomes and autosomes does a normal karyotype have?
- 23 pairs of chromosomes (46 total)
- 22 pairs of autosomes
- -> one is a sex chromosome