Nervous System I: Neurohistology Flashcards
what are the two components of the human nervous system?
- central nervous system (CNS)
- peripheral nervous system (PNS)
CNS components
- brain
- spinal cord
PNS components
- somatic (voluntary division)
- autonomic (involuntary division)
define neurons
- conducting elements (cells)
- makes up a part of the nervous system
define neuroglia
- accessory elements
- known as being supporting cells of the nervous system
define meninges
-coverings within the nervous system
neuron function
-responsible for receiving and transmitting information
classificational functions of neurons types
- sensory (afferent)
- motor (efferent)
- associative (interneuron)
neuron sensory function
-transmits impulse from periphery sensory recover to spinal cord or brain
neuron motor function
-transmits information from CNS to peripheral effectors
neuron motor function examples
- skeletal muscle
- smooth muscle
- cardiac muscle
- glands
neuron associative function
- located between sensory and motor neurons in CNS
- modifies responses of hormones
- relays information to other neurons
structural functions of neurons types
- multipolar
- bipolar
- unipolar
neuron multipolar structure
- has more than two processes attached to cell body
- most common type of neuron formed throughout CNS
neuron bipolar structure
- has two processes attached to cell body
- found in retina of eye and inner ear
neuron unipolar structure
- has only one process attached to cell body
- found in ganglia which are chapters of neurons adjacent to spinal cord
structure of typical neuron
- cell body
- processes (fibers) of a neuron
neuron cell body components
- most of the organelles typically found in cells (nucleus, mitochondria, golgi complex, etc)
- nissl bodies
- neurofibrils
neuron body: nissl bodies
- chomato philic bodies
- clusters of ribosomes of RER that module protein (neurotransmitters made of protein)
neuron body: neurofibrils
-cytoskeleton of neuron transport and maintain shape o neuron
neuron processes(fibers) of a neuron components
- dendrites
- axon (nerve fibers)
neuron fibers of a neuron: dendrites
- more than one per neuron
- receives impulse and transmits to cell body
neuron fibers of a neuron: axon
- only one per neuron
- transmits info away from the cell bud to another neuron or muscle
what are axons?
-nerve fibers
special characteristics of nerve fibers components
- myelin sheath
- neurolemma
- nodes of ranvier
- synaptic vesicles
special characteristics of nerve fibers: myelin sheath producer and location
produced by:
- oligodendrocytes in CNS
- schwann cells in PNS
special characteristics of nerve fibers: myelin sheath composition
-composed of primarily lipid(fat)
special characteristics of nerve fibers: myelin sheath function
-to increase transmission speed an electrical impulse
special characteristics of nerve fibers: neurolemma
-cell membrane of oligodendrocyte or schwann cell
special characteristics of nerve fibers: nodes of ranvier
- area of axon that’s not covered by myelin
- assists with rapid transmission of impulse
special characteristics of nerve fibers: synaptic vesicles
-structures that store neurotransmitters that are released at a synapse
allowers of communication in between neurons
- synapses
- conduction of nerve impulses
allower of communication in between neurons: synapse
- space between axon of a presynaptic neuron
- dendrite of postsynaptic neuron
allower of communication in between neurons: synapse components
- presynaptic neuron
- synaptic cleft
- postsynaptic neuron
allower of communication in between neurons: synapse: presynaptic neuron
-transmits impulse
allower of communication in between neurons: synapse: synaptic cleft
-space between the presynaptic axon and the dendrite of the postsynaptic dendrite
allower of communication in between neurons: synapse: postsynaptic neuron
-receives info
allower of communication in between neurons: conduction of nerve impulse characteristics
- resting membrane
- depolarization
- “wave of negativity”
- repolarization
allower of communication in between neurons: conduction of nerve impulse: resting membrane
- polarized
- positive charge outside cell membrane
- Na+ ions outside cell membrane
allower of communication in between neurons: conduction of nerve impulse: depolarization
- caused by influx of Na+ ions into cell
- negative charge on outside cell membrane
allower of communication in between neurons: conduction of nerve impulse: wave of negativity
-a wave of negativity travels along cell membrane
allower of communication in between neurons: conduction of nerve impulse: repolarization
-caused by influx of K+ ions to outside of cell
allower of communication in between neurons: conduction of nerve impulse: repolarization types of conduction
- continuous conduction
- stationary conduction
allower of communication in between neurons: conduction of nerve impulse: continuous conduction
-along myelinated axons; a continuous wave
allower of communication in between neurons: conduction of nerve impulse: stationary conduction
- conduction “jumps” along myelinated axon
- conducts only at nodes of ranvier (but more rapid)
types of nerve fibers
- A fibers
- B fibers
- C fibers
A fibers
- most heavily myelinated
- fast conduction
- sharp, stabbing pain
B fibers
- intermediate amount of myelin
- moderate speed
- moderate pain
C fibers
- least myelin (sometimes no myelin)
- slow speed
- dull, aching pain
define nuclei
-cluster of neurons in CNS
define ganglia
-cluster of neurons in PNS
define nerve
-bundles of axons in the PNS
define tract
-bundles of axons in the CNS
examples of neurotransmitters
- excitatory neurotransmitters
- inhibitory neurotransmitters
excitatory neurotransmitters components
- acetylcholine (Ach)
- norepinephrine (NE)
- serotonin
- dopamine
excitatory neurotransmitters: acetylcholine
-involved in muscle contraction and autonomics
excitatory neurotransmitters: norepinephrine
-involved in muscle contraction and autonomics
excitatory neurotransmitters: serotonin
- plays a role in constriction of smooth muscle
- regulates cyclic body processes
- contributes to mood(feelings of wellbeing and happiness)
excitatory neurotransmitters: dopamine
- helps control the brain’s reward and pleasure centers
- helps regulate movement and emotional responses
inhibitory neurotransmitters components
- gamma aminobutyric acid (GABA)
- enkephalin
- endorphins
- dopamine
inhibitory neurotransmitters: gamma aminobutyric acid
-responsible for regulation muscle tone; inhibitory
inhibitory neurotransmitters: enkephalin
- regulates pain perception on the body
- binds to opiate receptors in the body
inhibitory neurotransmitters: endorphins
- group of hormones similar to enkephalins
- activates body’s opiate receptors
- exerts an analgesic effect
inhibitory neurotransmitters: dopamine
- helps control the brain’s reward and pleasure centers
- helps regulate movement and emotional responses
what nervous system are acetylcholine and norepinephrine a part of?
-autonomic nervous system
excitatory neurotransmitter function
-causes depolarization of the postsynaptic neuron
inhibitory neurotransmitter function
-hyperpolarize the postsynaptic neuron preventing the transmission of the nerve impulse across the synapse
what is neuroglia also known as?
-“neural glue”
what system is the neuroglia a part of?
-central nervous system
neuroglia components
- oligodendrocyte
- microglia
- astrocyte
- ependymal cells
neuroglia oligodendrocyte
-cells that produces myelin covering (sheath) around axons in CNS
neuroglia microglia
-phagocytic cell that engulfs dead tissue
neuroglia astrocyte
- assists in the nourishment of neurons in CNS
- formation of the Blood-Brain Barrier
astrocyte blood brain barrier composition
- endothelium (lining of capillaries)
- basement membrane
- foot process of astrocytes
astrocyte blood brain barrier function
- regulates permeability of capillaries to control what enters brain
- prevents large molecules from entering brain
- keeps toxic substances from entering brain cells
neuroglia ependymal cells
-line the ventricles of the brain
define ventricles
-spaces within the brain
types of cells in peripheral nervous system
- schwann cell
- satellite cell
what is another name for schwann cells?
-neurolemmocytes
schwall cell
-produces myelin sheath around axon in PNS
satellite cell
-regulate nourishment to neuron bodies in the PNS