Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

boards and beyond > systemic lupus erythematous > Flashcards

systemic lupus erythematous Flashcards

1
Q

key finding in SLE

A

anti-nuclear antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

antibody-antigen complexes circulate in plasma and elicit

A

type III hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

antibody-antigen complexes activate

A

complement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

low levels of __ in SLE

A

C3/C4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

lupus specific antibodies

A

anti-double stranded DNA and anti-smith

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

lupus sensitive antibodies

A

anti nuclear antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

small nuclear ribonucleoprotein combine with RNA transcripts to form

A

spliceosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

spliceosome role

A

removes a portion of the RNA transcript

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

anti-smith antibody is directed toward

A

snRNP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

SLE flare sxs

A

fever, WL, fatigue, lymphadenopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

classic skin finding in lupus

A

malar rash

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Raynaud phenomenon

A

white/blue fingertips

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Raynaud phenomenon can lead to

A

fingertip ulcers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

other sxs of SLE

A

oral ulcers
arthritis
serositis (inflammation of pleura/pericardium)
penias (anemia, thrombocytopenia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

lupus cerebritis sxs

A

cognitive dysfunction, stroke, seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

lupus nephropathy

A

nephritic/nephrotic syndrome

17
Q

mc SLE renal syndrome

A

diffuse proliferative glomerular nephritis

18
Q

membranous glomerular nephritis

A

nephrotic syndrome

19
Q

cardiac manifestations

A

Libman-sacks (marantic) endocarditis

20
Q

__ antibodies occur in association with lupus

A

anti-phospholipid antibodies

21
Q

three imp clinical consequences of anti-phospholipid antibodies

A
  1. increased risk of venous/arterial thrombosis
  2. increased PTT
  3. false positive syphilis
22
Q

__ causes the false positive syphilis

A

anti-cardiolipin

23
Q

lupus anticoagulant interferes with

A

PTT test

24
Q

drug induced lupus classic drugs

A

INH
hydralazine
procainamide

25
Q

key features of drug induced lupus

A

anti-histone antibodies

26
Q

SLE treatment

A

steroids
avoid sunlight

27
Q

neonatal lupus sxs

A

rash
congenital complete heart block

28
Q

Libman-sacks endocarditis

A

nonbacterial inflammation of valves
classically affects both sides of mitral valve

boards and beyond (36 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions