sjogren's syndrome Flashcards
Sjögren’s syndrome is characterized by
destruction of salivary & lacrimal glands
sxs of SS
dry eyes, dry mouth
extra glandular disease sxs
dry skin
arthralgias
raynauds
SS is __ mediated
lymphocytic
what is seen on biopsy of SS
lymphocytic sialadenitis
SS is what type of hypersensitivity
type IV hypersensitivity
SS is associated with
rheumatoid arthritis
lupus
primary biliary cirrhosis
SS antibodies
anti-SS-A (Ro)
anti-SS-B (La)
schirmer test
tests reflex tear production
salivary gland scintigraphy
nuclear test
whole sialometry measures
saliva production
diagnosis of SS must include
histopathology & autoantibodies
pilocarpine moa
muscarinic agonists
increased risk of __ among sjogren’s
B cell lymphoma
B cell lymphoma may present as
unilateral swollen gland