sjogren's syndrome Flashcards

1
Q

Sjögren’s syndrome is characterized by

A

destruction of salivary & lacrimal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

sxs of SS

A

dry eyes, dry mouth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

extra glandular disease sxs

A

dry skin
arthralgias
raynauds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

SS is __ mediated

A

lymphocytic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is seen on biopsy of SS

A

lymphocytic sialadenitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SS is what type of hypersensitivity

A

type IV hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

SS is associated with

A

rheumatoid arthritis
lupus
primary biliary cirrhosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

SS antibodies

A

anti-SS-A (Ro)
anti-SS-B (La)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

schirmer test

A

tests reflex tear production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

salivary gland scintigraphy

A

nuclear test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

whole sialometry measures

A

saliva production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

diagnosis of SS must include

A

histopathology & autoantibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

pilocarpine moa

A

muscarinic agonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

increased risk of __ among sjogren’s

A

B cell lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

B cell lymphoma may present as

A

unilateral swollen gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly