coagulopathies

Question 1

bleeding time is a test of

Answer 1

platelet function

Question 2

normal activated partial thromboplastin time

Answer 2

30s

Question 3

normal prothrombin time

Answer 3

10s

Question 4

thrombin time

Answer 4

add thrombin to sample time to form clot

Question 5

abnormal platelets sxs

Answer 5

mucosal bleeding, skin bleeding, petechiae

Question 6

abnormal coagulation factors sxs

Answer 6

joint bleeding, deep tissue bleeding

Question 7

hemophilias genetics

Answer 7

x linked recessive diseases

Question 8

hemophilia A

Answer 8

def of factor VIII

Question 9

hemophilia B

Answer 9

def of factor IX

Question 10

hemophilias present with

Answer 10

spontaneous or easy bruising and recurrent joint bleeds

Question 11

screening for hemophilia

Answer 11

PTT will be prolonged

Question 12

PT, bleeding time, and platelet count will all be normal in

Answer 12

hemophilia

Question 13

desmopressin can be used to treat

Answer 13

mild hemophilia A

Question 14

desmopressin role increases

Answer 14

vWF and factor VIII levels and releases VIII from weibel-palade bodies

Question 15

desmopressin key side effects

Answer 15

flushing and HA

Question 16

aminocaproic acid use

Answer 16

antifibrinolytic drug

Question 17

aminocaproic acid moa

Answer 17

plasminogen activation to plasmin (less breakdown of clots)

Question 18

cryoprecipitate contains

Answer 18

factor VIII and fibrinogen

Question 19

cryoprecipitate is often used as source of

Answer 19

fibrinogen

Question 20

mixing study will differentiate

Answer 20

coagulation factor inhibitors from hemophilia A

Question 21

vit k def results in

Answer 21

bleeding

Question 22

key lab findings in vit k def

Answer 22

elevated PT/INR

Question 23

large volume blood transfusion cause

Answer 23

dilution of clotting factors

Question 24

packed RBCs are devoid of

Answer 24

plasma/platelets

Question 25

in liver disease loss of

Answer 25

clotting factors